The nature of relapse in schizophrenia

Table 1 Studies reporting symptom recurrence rates after treatment reduction/discontinuation after a single episode of psychosis

Authors	Sample size	Treatment duration		Symptom recurrence rates				Comparator recurrence rate
			9 months	12 months	18 months	24 months	36 months
Kane J et al. [24].	28	Not specified		41%				0%
Crow T et al. [26].	120	Not specified				62%		46%
Gitlin M et al. [21].	53	3 months in remission		78%		96%		-
Wunderink L et al. [25].	161	6 months in remission			43%			21%
Chen E. et al. [22].	178	12 months +		79%				41%
Gaebel W. et al. [27].	44	12 months		57%				4%
Boonstra G. et al. [23].	20	12 months min remission	82%					12%
Emsley R et al. [10].	33	24 months		79%		94%	97%	-