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Figure 1 | BMC Psychiatry

Figure 1

From: Methylphenidate in mania project (MEMAP): study protocol of an international randomised double-blind placebo-controlled study on the initial treatment of acute mania with methylphenidate

Figure 1

The vigilance regulation model of mania: Unstable vigilance induces a pathogenic circle with vigilance stabilisation syndrome leading to full-blown mania. Figure taken from: Hegerl U., et al. Are psychostimulants a treatment option in mania? Pharmacopsychiatry 2009; 42:169-174. Reproduced with kind permission of Georg Thieme Verlag KG”.

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