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Table 2 Patients’ clinical characteristics and HRQoL at enrolment (N = 637)

From: Compliance, persistence, costs and quality of life in young patients treated with antipsychotic drugs: results from the COMETA study

Description

Values

Non naïve (N = 574)

Naïve (N = 63)

p-value

Diagnosis:

    

Schizophrenia, n (%)

549 (86.2)

510 (88.9)

39 (61.9)

<0.0001*

Schizophreniform disorder, n (%)

88 (13.8)

64 (11.1)

24 (38.1)

 

Type of schizophrenia:

    

Catatonic, n (%)

7 (1.3)

7 (1.4)

0

0.661**

Disorganized, n (%)

56 (8.8)

51 (10.0)

5 (12.8)

 

Paranoid, n (%)

372 (67.8)

345 (67.6)

27 (69.2)

 

Undifferentiated, n (%)

88 (16.0)

81 (15.9)

7 (17.9)

 

Residual, n (%)

26 (4.1)

26 (5.1)

0

 

Duration of illness(years):

    

Mean (SD)

3.7 (3.0)

4.0 (3.0)

1.2 (2.5)

<0.0001‡

Diagnosis:

    

<1 year before, n (%)

175 (27.5)

128 (22.3)

48 (76.2)

<0.0001*

1–5.99 years before, n (%)

284 (44.6)

273 (47.6)

9 (14.3)

 

6–10 years before, n (%)

178 (27.9)

173 (30.1)

6 (9.5)

 

Age at onset of psychotic symptoms(years):

    

Mean (SD)

24.2 (5.5)

24.1 (5.5)

24.6 (5.9)

0.576‡

Age at first antipsychotic treatment(years):

    

Mean (SD)

25.5 (5.4)

25.5 (5.3)

26.1 (6.0)

0.370‡

Age at first hospitalization(years):

    

Mean (SD)

26.2 (5.4)

26.2 (5.4)

25.5 (5.8)

0.589‡

PANSS score

    

Positive subscale, Mean (SD)

17.3 (7.4)

16.9 (7.2)

21.6 (7.9)

<0.0001‡

Negative subscale, Mean (SD)

23.7 (8.5)

23.5 (8.5)

25.7 (8.3)

0.050‡

General subscale, Mean (SD)

45.6 (14.6)

44.8 (14.6)

52.7 (13.5)

<0.0001‡

Total, Mean (SD)

86.6 (27.4)

85.2 (27.1)

100.0 (26.2)

<0.0001‡

GAF score:

    

Mean (SD)

54.1 (13.8)

54.6 (13.9)

49.6 (12.6)

0.007‡

CGI-S score:

    

Mean (SD)

4.3 (2.2)

4.3 (1.1)

4.6 (0.9)

0.011‡

EQ-5D VAS

    

Mean (SD)

63.5 (17.9)

63.5 (17.9)

63.5 (18.2)

0.991‡

EQ-5D utility score

    

Mean (SD)

0.71 (0.3)

0.70 (0.3)

0.72 (0.3)

0.656‡

SF-36 PCS

    

Mean (SD)

47.5 (9.3)

47.5 (9.4)

47.4 (9.2)

0.928‡

SF-36 MCS

    

Mean (SD)

39.0 (9.6)

39.3 (9.5)

36.6 (10.4)

0.049‡

  1. * A Chi-square test was applied.
  2. ** A Fisher’s exact test was applied.
  3. ‡ An independent sample Student’s t-test was applied.
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BMC Psychiatry

ISSN: 1471-244X

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