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Table 6 Results of the ROC-analysis with panic disorder/agoraphobia/social phobia as outcome variable

From: To what extent does the anxiety scale of the Four-Dimensional Symptom Questionnaire (4DSQ) detect specific types of anxiety disorder in primary care? A psychometric study

Study A B C D E Pooled A-E
Total numbers 295 170 118 156 230 969
Prevalencea 19.0% 16.5% 50.0% 48.7% 42.6% 32.7%
AUCb (95% CI) .851 (.803; .896) .857 (.774; .927) .737 (.643; .820) .787 (.714; .855) .775 (.714; .834) .793 (.763; .822)
Best thresholdc (95% CI) 7.5 (5.5; 8.5) 8.5 (4.5; 12.5) 5.5 (4.5; 8.5) 4.5 (3.5; 6.5) 7.5 (6.5; 11.5) 6.5 (5.5; 7.5)
- Sensitivity (95% CI) .79 (.68; .89) .71 (.54; .86) .71 (.59; .83) .75 (.64; .84) .79 (.70; .86) .74 (.69; .79)
- Specificity (95% CI) .77 (.72; .83) .84 (.77; .89) .63 (.51; .75) .73 (.63; .83) .67 (.59; .75) .71 (.67; .75)
- ppvd (95% CI) .45 (.39; .52) .47 (.36; .59) .63 (.58; .75) .72 (.65; .80) .64 (.58; .70) .55 (.52; .59)
- npve (95% CI) .94 (.91; .97) .94 (.90; .97) .69 (.60; .78) .75 (.68; .83) .81 (.75; .87) .85 (.82; .87)
Lower thresholdf (95% CI) 5.5 (3.5; 7.5) 4.5 (1.5; 8.5) 2.5 (1.5; 4.5) 1.5 (0.5; 3.5) 3.5 (2.5; 7.5) 3.5 (2.5; 4.5)
- Sensitivity (95% CI) .86 (.75; .95) .89 (.79; 1.00) .88 (.80; .97) .91 (.84; .96) .87 (.80; .93) .87 (.83; .90)
- Specificity (95% CI) .68 (.62; .74) .62 (.54; .70) .37 (.25; .49) .43 (.31; .54) .42 (.33; .50) .51 (.47; .55)
- ppvd (95% CI) .39 (.34; .44) .32 (.27; .37) .58 (.53; .64) .60 (.55; .65) .52 (.49; .57) .46 (.44; .49)
- npve (95% CI) .95 (.92; .98) .97 (.93; 1.00) .76 (.61; .91) .83 (.72; .93) .81 (.73; .89) .89 (.86; .92)
Higher thresholdg (95% CI) 10.5 (8.5; 11.5) 9.5 (7.5; 11.5) 9.5 (7.5; 12.5) 8.5 (6.5; 12.5) 15.5 (11.5; 17.5) 10.5 (9.5; 11.5)
- Sensitivity (95% CI) .57 (.45; .70) .64 (.46; .82) .42 (.31; .56) .50 (.38; .61) .43 (.32; .52) .52 (.46; .57)
- Specificity (95% CI) .89 (.85; .93) .86 (.80; .92) .86 (.78; .95) .89 (.81; .95) .87 (.81; .92) .86 (.83; .89)
- ppvd (95% CI) .54 (.45; .65) .47 (.36; .61) .76 (.63; .89) .81 (.71; .91) .71 (.61; .82) .65 (.59; .70)
- npve (95% CI) .90 (.87; .93) .92 (.89; .96) .60 (.54; .66) .65 (.60; .71) .67 (.63; .71) .79 (.77; .81)
  1. aPrevalence of panic disorder/agoraphobia/social phobia.
  2. bArea under the ROC curve.
  3. cThreshold closest to top-left corner of ROC graph (i.e., sensitivity = 1, (1-specificity) = 0).
  4. dPositive predictive value.
  5. eNegative predictive value.
  6. fLower threshold = highest threshold with sensitivity ≥0.85.
  7. gHigher threshold = lowest threshold with specificity ≥0.85.