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Table 6 Results of the ROC-analysis with panic disorder/agoraphobia/social phobia as outcome variable

From: To what extent does the anxiety scale of the Four-Dimensional Symptom Questionnaire (4DSQ) detect specific types of anxiety disorder in primary care? A psychometric study

Study

A

B

C

D

E

Pooled A-E

Total numbers

295

170

118

156

230

969

Prevalencea

19.0%

16.5%

50.0%

48.7%

42.6%

32.7%

AUCb (95% CI)

.851 (.803; .896)

.857 (.774; .927)

.737 (.643; .820)

.787 (.714; .855)

.775 (.714; .834)

.793 (.763; .822)

Best thresholdc (95% CI)

7.5 (5.5; 8.5)

8.5 (4.5; 12.5)

5.5 (4.5; 8.5)

4.5 (3.5; 6.5)

7.5 (6.5; 11.5)

6.5 (5.5; 7.5)

- Sensitivity (95% CI)

.79 (.68; .89)

.71 (.54; .86)

.71 (.59; .83)

.75 (.64; .84)

.79 (.70; .86)

.74 (.69; .79)

- Specificity (95% CI)

.77 (.72; .83)

.84 (.77; .89)

.63 (.51; .75)

.73 (.63; .83)

.67 (.59; .75)

.71 (.67; .75)

- ppvd (95% CI)

.45 (.39; .52)

.47 (.36; .59)

.63 (.58; .75)

.72 (.65; .80)

.64 (.58; .70)

.55 (.52; .59)

- npve (95% CI)

.94 (.91; .97)

.94 (.90; .97)

.69 (.60; .78)

.75 (.68; .83)

.81 (.75; .87)

.85 (.82; .87)

Lower thresholdf (95% CI)

5.5 (3.5; 7.5)

4.5 (1.5; 8.5)

2.5 (1.5; 4.5)

1.5 (0.5; 3.5)

3.5 (2.5; 7.5)

3.5 (2.5; 4.5)

- Sensitivity (95% CI)

.86 (.75; .95)

.89 (.79; 1.00)

.88 (.80; .97)

.91 (.84; .96)

.87 (.80; .93)

.87 (.83; .90)

- Specificity (95% CI)

.68 (.62; .74)

.62 (.54; .70)

.37 (.25; .49)

.43 (.31; .54)

.42 (.33; .50)

.51 (.47; .55)

- ppvd (95% CI)

.39 (.34; .44)

.32 (.27; .37)

.58 (.53; .64)

.60 (.55; .65)

.52 (.49; .57)

.46 (.44; .49)

- npve (95% CI)

.95 (.92; .98)

.97 (.93; 1.00)

.76 (.61; .91)

.83 (.72; .93)

.81 (.73; .89)

.89 (.86; .92)

Higher thresholdg (95% CI)

10.5 (8.5; 11.5)

9.5 (7.5; 11.5)

9.5 (7.5; 12.5)

8.5 (6.5; 12.5)

15.5 (11.5; 17.5)

10.5 (9.5; 11.5)

- Sensitivity (95% CI)

.57 (.45; .70)

.64 (.46; .82)

.42 (.31; .56)

.50 (.38; .61)

.43 (.32; .52)

.52 (.46; .57)

- Specificity (95% CI)

.89 (.85; .93)

.86 (.80; .92)

.86 (.78; .95)

.89 (.81; .95)

.87 (.81; .92)

.86 (.83; .89)

- ppvd (95% CI)

.54 (.45; .65)

.47 (.36; .61)

.76 (.63; .89)

.81 (.71; .91)

.71 (.61; .82)

.65 (.59; .70)

- npve (95% CI)

.90 (.87; .93)

.92 (.89; .96)

.60 (.54; .66)

.65 (.60; .71)

.67 (.63; .71)

.79 (.77; .81)

  1. aPrevalence of panic disorder/agoraphobia/social phobia.
  2. bArea under the ROC curve.
  3. cThreshold closest to top-left corner of ROC graph (i.e., sensitivity = 1, (1-specificity) = 0).
  4. dPositive predictive value.
  5. eNegative predictive value.
  6. fLower threshold = highest threshold with sensitivity ≥0.85.
  7. gHigher threshold = lowest threshold with specificity ≥0.85.