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Table 3 Comparisons between control and intervention conditions on physical, cardiovascular, cognitive, functional and life quality measures

From: A complex multimodal activity intervention to reduce the risk of dementia in mild cognitive impairment–ThinkingFit: pilot and feasibility study for a randomized controlled trial

Physical health measures

 

N

T0

T1

T2

F

p

Systolic BP (mmHg)

53

145.1 (14.2)a

144.4 (15.0)b

135.8 (15.7)a,b

17.1

<.001

Diastolic BP (mmHg)

53

75.4 (16.2)

78.2 (9.4)

74.3 (9.0)

3.1

.07

BMI (kg/m2)

52

26.3 (3.6)a

26.2 (3.5)b

25.9 (3.4)a,b

7.0

<.005

Cardiovascular fitness measures

Resting heart rate (beats/min)

53

68.2 (10.7)a

69.6 (13.1)b

64.6 (10.2)a,b

11.0

<.001

1 minute recovery heart rate (beats/min)

52

74.8 (14.0)a

75.6 (15.2)b

68.8 (11.8)a,b

14.2

<.001

Cognitive measures

Forward digit span

43

9.4 (2.1)a

9.5 (2.4)

10.0 (2.3)a

3.4

<.05

Backwards digit span

43

5.3 (2.1)a

5.3 (2.0)b

6.3 (2.3)a,b

8.6

<.001

TMT-A (sec)

41

50.0 (21.1)

45.5 (19.3)

45.9 (19.3)

2.6

.09

TMT-B (sec)

43

184.5 (138.0)

192.0 (137.0)

146.3 (124.9)

2.6

.09

Letter fluency

43

14.1 (4.8)a

14.6 (7.3)

16.3 (5.7)a

3.4

.053

Category fluency

43

12.7 (4.6)a

10.5 (4.5)a,b

13.0 (4.7)b

7.8

.001

Quality of life and functional abilities

WHO-QOL total

52

256 (38)

252 (43)a

263 (37)a

3.3

<.05

ADCS-MCI-ADL

53

45.2 (4.9)

44.7 (5.4)

45.5 (7.6)

0.5

.54

  1. The table shows data for the control period (T0 to T1) and intervention period (T1 to T2). Data are mean (standard deviation). a and b denote pairs that differ significantly at p < .05.