|
Overall mean weighted
OR
|
OR (95% CI) p
two-tailed
|
1.24 (1.06-1.45) .006*
|
1.68 (1.23-2.31) .001*
|
1.68 (1.17-2.40) .004*
|
|
Heterogeneity statistics
|
Q(df)
p
two-tailed
I
2
|
30 (14) .009* 53%
|
55 (12) <.0001* 78%
|
8 (4) .091 50%
|
|
One-study removed analysis (Additional file
1
: Figure S1)
|
Which studies, removed one at a time from the analysis, remove the significance of the overall mean weighted OR?
|
None
|
None
|
Cheung et al., 2010 [36]
|
|
Cumulative analysis (1993 to 2013) (Additional file
1
: Figure S2)
|
Which studies, added to all previous studies one at a time, remove the significance of the overall mean weighted OR?
|
Crum et al., 1993 [38]; Fergusson et al., 1996 [42]
|
Degenhardt et al., 2001 [39]
|
NPMS, 2007 [10]
|
|
Rosenthal’s Fail-safe
N
for
p > .05
|
N studies needed to remove the significance of the overall mean weighted OR (N studies missing for every study in meta-analysis needed to remove the significance of the overall mean weighted OR)
|
N=49 (49/15 = 3)
|
N=105 (105/13 = 8)
|
N=17 (17/5 = 3)
|
|
Duval and Tweedie’s Trim-and-Fill analysis
|
Funnel plot symmetrical? N studies missing on either side of the overall mean weighted OR
|
YES
|
YES
|
YES
|
|
N=0
|
N=0
|
N=0
|
|
Begg and Mazumdar Rank Order Correlation
|
τ
|
.13
|
-.19
|
-.30
|
|
p
two-tailed
|
.488
|
.360
|
.462
|
|
Egger’s regression
|
intercept
|
.25
|
1.73
|
−4.05
|
| |
p
two-tailed
|
.748
|
.005*
|
.415
|
