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Table 2 Statistical tests for the social cognition mediation in neurocognition- symptomatology relation

From: The relationship between neurocognition and symptomatology in people with schizophrenia: social cognition as the mediator

Neurocognitive functioning- social cognitive functioning

Psychiatric symptoms

A Estimate (P-value)

B Estimate (P-value)

C Estimate (P-value)

C’ Estimate (P-value)

Indirect effect (Lower limit 95% CI, upper limit 95% CI)

Effect size of the indirect effect

Controlling for education, age and sex

A Estimate (P-value)

B Estimate (P-value)

C Estimate (P-value)

C’ Estimate (P-value)

Indirect effect (Lower limit 95% CI, upper limit 95% CI)

Perception- ToM

Negative symptoms

0.36** (0.0053)

-0.99* (0.0227)

-0.97* (0.0201)

-0.62 (0.1469)

-0.3553 (-0.9668, -0.0480)

0.0603

 

0.33* (0.0274)

-0.97* (0.0302)

-1.03* (0.0334)

-0.71 (0.1399)

-0.3159 (-1.0705, -0.0077)

Executive functioning - ToM

 

0.26* (0.0200)

-1.03* (0.0159)

-0.78* (0.0290)

-0.52 (0.1464)

-0.2667 (-0.6880, -0.0518)

0.0498

 

0.23* (0.0405)

-0.99* (0.0266)

-0.76* (0.0405)

-0.53 (0.1491)

-0.2279 (-0.6625, -0.0149)

Perception- ToM

Positive symptoms

0.36** (0.0053)

-0.62* (0.0520)

-0.14 (0.6448)

0.08 (0.7849)

-0.2199 (-0.6595, -0.0223)

0.0026

 

0.33* (0.0274)

-0.64* (0.0530)

-0.20 (0.5676)

0.01 (0.9804)

-0.2071 (-0.7150, 0.0044)

Executive functioning - ToM

 

0.26* (0.0200)

-0.49 (0.1097)

-0.39 (0.1158)

-0.27 (0.2991)

-0.1261 (-0.3579, -0.0118)

0.0254

 

0.23* (0.0405)

-0.54 (0.0947)

-0.42 (0.1129)

-0.29 (0.2743)

-0.1238 (-0.3888, -0.0027)

Perception – ToM

General symptoms

0.36** (0.0053)

-0.55 (0.1300)

-0.53 (0.1256)

-0.32 (0.3659)

-0.1978 (-0.6631, 0.0324)

0.0275

 

0.33* (0.0274)

-0.53 (0.1554)

-0.65 (0.1030)

-0.47 (0.2469)

-0.1735 (-0.7176, 0.0364)

Executive functioning - ToM

 

0.26* (0.0200)

-0.46 (0.1797)

-0.69* (0.0162)

-0.57* (0.0545)

-0.1204 (-0.3798, 0.0361)

0.0377

 

0.23* (0.0405)

-0.46 (0.2045)

-0.71* (0.0169)

-0.60* (0.0477)

-0.1061 (-0.4127, 0.0351)

  1. Note: (A) Regression slope of neurocognitive functioning predicting social cognitive functioning; (B) regression slope of social cognitive functioning predicting psychiatric symptoms, controlling for neurocognitive functioning; (C) regression slope of neurocognitive functioning predicting psychiatric symptoms; (C’) regression slope of neurocognitive functioning predicting psychiatric symptoms, controlling for social cognitive functioning. Bootstrapping was used to estimate indirect effects (Shrout & Bolger, 2002).
  2. *P < = 0.05.
  3. **P < =0.01.
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BMC Psychiatry

ISSN: 1471-244X

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