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Table 1 Demographic and disease characteristics of the bipolar disorder patients in the euthymic state

From: Olanzapine is superior to lamotrigine in the prevention of bipolar depression: a naturalistic observational study

  Olanzapine (n = 20) Lamotrigine (n = 26)
Age (years), mean (SD) 43.5 (11.8) 38.8 (11.5)
Female, n (%) 11 (55.0) 21 (80.8)
Age of onset, mean (SD) 33.0 (11.7) 27.4 (7.6)
Polarity of first onset   
Manic, Mixed episode or others, n (%) 7 (35.0) 4 (15.4)
Depressive episode, n (%) 13 (65.0) 22 (84.6)
Diagnosis as Bipolar I disorder, n (%)a 13 (65.0)* 5 (19.2)*
Polarity of previous episodeb   
Manic, Mixed episode or others, n (%) 13 (65.0) 4 (15.4)*
Depressive episode, n (%) 7 (35.0) 22 (84.6)*
With residual affective symptoms, n (%) 9 (45) 8 (30.8)
Weeks of euthymic state before enrolment, mean (SD) 13.1 (8.9) 10.8 (5.8)
Number of depressive episodes, past year, mean (SD) 0.3 (0.4) 0.5 (0.6)
Number of manic, mixed episodes or others, past year, mean (SD) 0.3 (0.5) 0.2 (0.5)
Comorbid personality disorder, n (%) 3 (15.0) 9 (34.6)
Comorbid alcohol abuse/dependence, n (%) 4 (20.0) 4 (15.4)
Comorbid other psychiatric disorder (posttraumatic stress disorder, panic disorder) or medical diseases, n (%) 4 (20.0) 1 (3.8)
Dosage (mg/day), mean (SD) 10.9 (7.4) 86.5 (49.6)
Concomitant medications, n (%)   
Antidepressant(s)c 6 (30.0)* 18 (69.2)*
Anxiolytic(s) 7 (35.0) 16 (61.5)
Short-acting hypnotics 20 (100) 21 (80.8)
Long acting hypnotics 12 (60.0) 17 (65.4)
Present YMRS scored 6.3 (5.0) 3.3 (3.7)*
Present HAM-D score 4.8 (1.1) 5.2 (1.0)
  1. Abbreviations: YMRS Young’s Mania Rating Scale, HAM-D Hamilton Depression Rating Scale.
  2. *p < .01; aχ2 = 9.94, p = .002; bχ2 = 11.94, p = .001; cχ2 = 6.97, p = .008; dt-test = 2.32, p = .025.