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Table 2 Major outcome of the one-year follow up study, n (%)

From: Olanzapine is superior to lamotrigine in the prevention of bipolar depression: a naturalistic observational study

  Olanzapine (n = 20) Lamotrigine (n = 26) p value
Recurrence definition
Mania 3 (15.0) 0 ( 0) 0.075a
Symptomatic recurrenceb 1 (5.0)   0.435a
Syndromic recurrencec 2 (10.0)   0.184a
Depression 4 (20.0) 15 (57.7) 0.010*
Symptomatic recurrenceb 3 (15.0) 9 (34.6) 0.133
Syndromic recurrencec 1 (5.0) 6 (23.1) 0.119a
Any mood episode 7 (35.0) 15 (57.7) 0.127
Symptomatic recurrenceb 4 (20.0) 9 (34.6) 0.275
Syndromic recurrencec 3 (15.0) 6 (23.1) 0.711a
  1. *p < .05.
  2. aFisher’s exact test.
  3. bScore ≥ 12 on Young’s Mania Rating Scale or ≥ 7 on Hamilton Depression Rating Scale, or if the patient’s condition required an increase in the dosage of olanzapine or lamotrigine.
  4. cThe patient’s condition met the DSM-IV-TR criteria for manic or depressive episode or the patient had active suicide ideation.