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Table 2 Major outcome of the one-year follow up study, n (%)

From: Olanzapine is superior to lamotrigine in the prevention of bipolar depression: a naturalistic observational study

 

Olanzapine (n = 20)

Lamotrigine (n = 26)

p value

Recurrence definition

Mania

3 (15.0)

0 ( 0)

0.075a

Symptomatic recurrenceb

1 (5.0)

 

0.435a

Syndromic recurrencec

2 (10.0)

 

0.184a

Depression

4 (20.0)

15 (57.7)

0.010*

Symptomatic recurrenceb

3 (15.0)

9 (34.6)

0.133

Syndromic recurrencec

1 (5.0)

6 (23.1)

0.119a

Any mood episode

7 (35.0)

15 (57.7)

0.127

Symptomatic recurrenceb

4 (20.0)

9 (34.6)

0.275

Syndromic recurrencec

3 (15.0)

6 (23.1)

0.711a

  1. *p < .05.
  2. aFisher’s exact test.
  3. bScore ≥ 12 on Young’s Mania Rating Scale or ≥ 7 on Hamilton Depression Rating Scale, or if the patient’s condition required an increase in the dosage of olanzapine or lamotrigine.
  4. cThe patient’s condition met the DSM-IV-TR criteria for manic or depressive episode or the patient had active suicide ideation.
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BMC Psychiatry

ISSN: 1471-244X

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