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Table 2 Logistic regression analysis of the adiposity measurements associated with probable major depression

From: Gender differences in the association between adiposity and probable major depression: a cross-sectional study of 140,564 UK Biobank participants

   Overall Women Men
  Model 1 Model 2 Model 1 Model 2 Model 1 Model 2
N = Overall (women, men) OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value OR (95% CI) P-value
BMI category              
Underweight 654 (517, 137) 1.00 (0.83, 1.20) 0.972 0.93 (0.77, 1.13) 0.480 0.92 (0.74, 1.13) 0.428 0.89 (0.71, 1.10) 0.281 1.47 (0.98, 2.21) 0.061 1.25 (0.82, 1.93) 0.302
Normal-weight 46,121 (29748,16373) 1 - 1 - 1 - 1 - 1 - 1 -
Overweight 59,932 (27380, 32552) 1.15 (1.11, 1.18) <0.001 1.09 (1.06, 1.13) <0.001 1.20 (1.15, 1.24) <0.001 1.14 (1.10, 1.19) <0.001 1.07 (1.01, 1.12) 0.018 1.02 (0.97, 1.08) 0.480
Obese (overall) 33,857 (17448, 16409) 1.36 (1.32, 1.41) <0.001 1.16 (1.12, 1.20) <0.001 1.43 (1.37, 1.50) <0.001 1.24 (1.19, 1.30) <0.001 1.24 (1.17, 1.32) <0.001 1.05 (0.99, 1.12) 0.134
 Class I 24,458 (11634, 12824) 1.29 (1.24, 1.34) <0.001 1.12 (1.08, 1.17) <0.001 1.35 (1.29, 1.42) <0.001 1.20 (1.14, 1.26) <0.001 1.18 (1.11, 1.26) <0.001 1.02 (0.96, 1.10) 0.489
 Class II 6,852 (4089, 2763) 1.47 (1.38, 1.56) <0.001 1.21 (1.14, 1.29) <0.001 1.51 (1.41, 1.63) <0.001 1.29 (1.20, 1.40) <0.001 1.38 (1.25, 1.53) <0.001 1.10 (0.99, 1.23) 0.081
 Class III 2,547 (1725, 822) 1.82 (1.66, 1.98) <0.001 1.39 (1.27, 1.53) <0.001 1.84 (1.66, 2.04) <0.001 1.48 (1.32, 1.65) <0.001 1.76 (1.50, 2.08) <0.001 1.29 (1.08, 1.54) 0.006
WC category              
Normal-weight 56,210 (29235, 26975) 1 - 1 - 1 - 1 - 1 - 1 -
Overweight 37,850 (18932, 18918) 1.13 (1.10, 1.17) <0.001 1.07 (1.03, 1.10) <0.001 1.15 (1.10, 1.20) <0.001 1.09 (1.04, 1.14) <0.001 1.11 (1.05, 1.17) 0.096 1.04 (0.98, 1.10) 0.161
Obese 46,504 (26926, 19578) 1.34 (1.30, 1.39) <0.001 1.15 (1.11, 1.19) <0.001 1.39 (1.33, 1.44) <0.001 1.21 (1.16, 1.26) <0.001 1.28 (1.22, 1.35) <0.001 1.07 (1.02, 1.13) 0.010
WHR category              
Normal-weight 50,725 (31941, 18784) 1 - 1 -   - 1 - 1 - 1 -
Overweight 56,790 (19336, 37454) 1.14 (1.10, 1.18) <0.001 1.05 (1.02, 1.09) 0.002 1.12 (1.08, 1.17) <0.001 1.05 (1.01, 1.10) 0.024 1.18 (1.13, 1.24) <0.001 1.06 (1.01, 1.12) 0.018
Obese 33,049 (23816, 9233) 1.30 (1.26, 1.35) <0.001 1.09 (1.05, 1.13) <0.001 1.26 (1.21, 1.31) <0.001 1.09 (1.04, 1.13) <0.001 1.46 (1.36, 1.56) <0.001 1.12 (1.04, 1.20) 0.002
BF% category              
Normal-weight 10,186 (3829, 6357) 1 - 1 - 1 - 1 - 1 - 1 -
Overweight 39,212 (14774, 24438) 1.07 (1.01, 1.14) 0.016 1.06 (1.00, 1.13) 0.039 1.08 (1.00, 1.18) 0.061 1.10 (1.00, 1.20) 0.039 1.06 (0.98, 1.14) 0.156 1.03 (0.95, 1.12) 0.469
Obese 91,166 (56490, 34676) 1.32 (1.25, 1.40) <0.001 1.18 (1.12, 1.25) <0.001 1.37 (1.26, 1.48) <0.001 1.26 (1.16, 1.37) <0.001 1.27 (1.17, 1.36) <0.001 1.09 (1.00, 1.18) 0.038
  1. OR: Odds ratio; CI: Confidence Interval; Model 1: adjusted by age, sex, socio-economic status, and ethnicity; Model 2 (full adjusted): in addition to the variables in model-1 below variables were added: employment, alcohol consumption, smoking, comorbidity (CVD, diabetes, hypertension, cancer), and use of psychotropic medications; BMI: body mass index category (kg/m2); underweight (<18.5), normal-weight (18.5-24.9), overweight (25–29.9), obese overall (>30), class I (30–34), class II (35–39), and class III (>40); WC: Waist Circumference category (cm) men/women; normal-weight (<94/<80), overweight (94-101/80-87), obese (≥102/≥88); WHR: Waist-to-hip ratio category men/women; normal-weight (<0.90/<0.80), overweight (0.90-0.99/0.80-0.84), obese (≥1/≥0.85); BF: Body fat (%) men/women; normal-weight (<18/<25), overweight (18-25/25-32), obese (>25/>32).