Skip to main content

Table 2 Descriptive characteristics in association studies on G-703 T/A473T/G19918A TPH-2 gene variants and SB by populations

From: Association of TPH-1 and TPH-2 gene polymorphisms with suicidal behavior: a systematic review and meta-analysis

Reference

Location

Diagnosis

Number of males

Number

Genotypes

Alleles

P for HWE

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

       

GG/TG/TT

GG/TG/TT

T/G

T/G

  

Caucasian population (G-703 T TPH-2 variant)

Zhou Z. et al., 2005 [61]

USA

SA and major depression

150

196

150

196

106/40/4

132/58/6

252/48

322/70

1.00

1.00

Zill P. et al., 2007 [60]

Germany

SA and alcoholism

-

164

102

305

61/36/5

191/101/13

158/46

483/127

1.00

1.00

Stefulj J. et al., 2011 [57]

Croatia

SC

291

280

291

280

181/96/14

183/80/17

458/124

446/114

0.06

0.72

       

348/172/23

506/239/36

  

0.78

0.26

Asian population (G-703 T TPH-2 variant)

Mouri K. et al., 2009 [58]

Japan

SC

156

162

234

260

62/117/55

80/128/52

241/227

288/232

1.00

1.00

Yoon H.K. et al., 2008 [44]

Korea

SA and major depression

82

80

181

176

58/81/42

34/82/60

197/165

150/202

0.18

0.53

       

120/198/97

114/210/112

  

0.37

0.44

Reference

Location

Diagnosis

Number of males

Number

Genotypes

Alleles

P for HWE

Cases

Cases

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

       

AA/AT/TT

AA/AT/TT

A/T

A/T

  

Caucasian population (A-473 T TPH-2 variant)

Zhou Z. et al., 2005 [61]

USA

SA and major depression

150

196

150

196

0/14/136

0/15/181

14/286

15/377

1.00

1.00

Zupanc T.et al., 2011 [19]

Slovenia

SC and alcoholism

-

-

383

222

0/42/341

2/31/189

42/724

35/409

0.61

0.63

       

0/56/177

2/46/370

  

0.36

0.65

Asian population (A-473 T TPH-2 variant)

Mouri K.et al., 2009 [58]

Japan

SC

156

162

234

260

2/44/188

3/48/209

48/420

54/466

1.00

0.74

Reference

Location

Diagnosis

Number of males

Number

Genotypes

Alleles

P for HWE

Cases

Cases

Cases

Controls

Cases

Controls

Cases

Controls

Cases

Controls

       

GG/GA/AA

GG/GA/AA

G/A

G/A

  

Caucasian population ( G19918A TPH-2 variant)

Zill P. et al.,2004 [20]

Germany

SC

191

138

263

266

195/63/5

166/88/12

453/73

420/112

1.00

1.00

Zill P. et al.,2007 [60]

Germany

SA and alcoholism

-

164

102

305

4/31/67

12/98/195

39/165

122/488

0.75

1.00

Must A. et al., 2009 [59]

Estonia

SC

298

327

288

327

206/75/7

242/79/6

487/89

563/91

1.00

1.00

Buttenschon H.N. et al.,2013 [41]

Denmark

SC

209

763

553

1033

396/150/7

743/268/22

942/169

1754/312

0.09

0.08

       

801/319/86

1163/533/235

  

0.06

0.09

Asian population ( G19918A TPH-2 variant)

K. Mouri et al.2009 [58]

Japan

SC

156

162

234

260

219/15/0

239/21/0

453/234

499/260

1.00

1.00

  1. SA = Suicide attempt, SI = Suicide ideation, and SC = Suicide completion.