Table 4 Meta-analysis of case–control studies on G-703 T/ A-473 T/G19918A TPH-2 gene variants and SB by populations

Caucasian population

Allelic

With heterogeneity

0.95(0.79-1.14)

0.95(0.79-1.14)

0.91

0.72

0.95(0.79-1.14)

0.95(0.79-1.14)

0.91

0.72

1.12(0.88-1.43)

1.09(0.95-1.25)

0.04

0.59

Without heterogeneity

0.99(0.85-1.16)

0.99(0.851.16)

0.52

0.57

Additive

With heterogeneity

1.03(0.66-1.62)

1.03(0.6-61.62)

0.84

0.56

1.03(0.66-1.62)

1.03(0.66-1.62)

0.84

0.56

1.45(0.87-2.40)

1.45(0.87-2.40)

0.44

0.95

Without heterogeneity

Dominant

With heterogeneity

1.05(0.68-1.62)

1.05(0.68-1.62)

0.79

0.79

1.05(0.68-1.62)

1.05(0.68-1.62)

0.79

0.79

1.18(0.79-1.76)

1.14(0.80-1.64)

0.35

0.33

Without heterogeneity

Recessive

With heterogeneity

0.91(0.72-1.15)

0.91(0.72-1.15)

0.86

0.54

0.91(0.72-1.15)

0.91(0.72-1.15)

0.86

0.54

1.15(0.86-1.55)

1.09(0.93-1.29)

0.06

0.59

Without heterogeneity

0.98(0.81-1.18)

0.98(0.81-1.18)

0.60

0.52

Asian population

Allelic

With heterogeneity

1.08(0.78-1.50)

1.08(0.92-1.27)

0.01

0.93

Without heterogeneity

0.91(0.75-1.11)

0.91(0.75-1.11)

0.47

0.58

Additive

With heterogeneity

1.14(0.57-2.27)

1.14(0.81-1.60)

0.01

0.99

Without heterogeneity

0.78(0.51-1.17)

0.78(0.511.17)

0.78

0.29

Dominant

With heterogeneity

1.09(0.82-1.44)

1.09(0.82-1.44)

0.11

0.94

Without heterogeneity

Recessive

With heterogeneity

1.13 (0.74-1.70)

1.11(0.87-1.41)

0.03

0.86

Without heterogeneity

0.93(0.70-1.22)

0.93(0.70-1.22)

0.48

0.94