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Table 2 Regions of reduced white matter FA in adolescent GAD patients compared with healthy controls (p < 0.05, TFCE-corrected)

From: White matter abnormalities in adolescents with generalized anxiety disorder: a diffusion tensor imaging study

Cluster index Anatomic location L/R Cluster size Peak coordinates
     x y z
1 Uncinate fasciculus, Inferior fronto-occipital fasciculus, Inferior longitudinal fasciculus, Superior corona radiate, Anterior limb of internal capsule, Superior longitudinal fasciculus L 2778 −40 −15 −13
2 Uncinate fasciculus, Inferior fronto-occipital fasciculus, Inferior longitudinal fasciculus, Posterior corona radiate, Posterior limb of internal capsule R 1766 28 −17 23
3 Uncinate fasciculus, Inferior fronto-occipital fasciculus R 346 30 11 −8
4 Inferior fronto-occipital fasciculus, Posterior corona radiata L 187 −33 −50 12
5 Uncinate fasciculus, Inferior fronto-occipital fasciculus L 187 −38 17 −15
6 Inferior longitudinal fasciculus, Anterior corona radiate L 130 −27 −50 20
7 Inferior longitudinal fasciculus, Inferior fronto-occipital fasciculus L 111 −31 −43 −16
  1. FA, Fractional anisotropy; GAD, Generalized anxiety disorder; TFCE, The threshold-free cluster enhancement; L/R, Left/right.