Hypothalamic-pituitary-adrenal axis functioning and dysfunctional attitude in depressed patients with and without childhood neglect

Table 2 Differences in HPA axis functioning, DAS scores between any two groups of healthy control groups, depressed groups with and without childhood neglect

Comparison between the two groups		HPA axis functioning (nmol/l)	p	DAS	p
CWOCN		6.82 ± 2.81		114.21 ± 21.38
	DWCN	8.76 ± 2.43	0.067	159.72 ± 31.28	0.000
	DWOCN	4.84 ± 2.73	0.048	139.17 ± 28.87	0.000
	CWCN	7.68 ± 1.66	0.29	142.20 ± 26.3	0.000
DWCN		8.76 ± 2.43		159.72 ± 31.28
	DWOCN	4.84 ± 2.73	0.000	139.17 ± 28.87	0.000
	CWCN	7.68 ± 1.66	0.59	142.20 ± 26.3	0.006
DWOCN		4.84 ± 2.73		139.17 ± 28.87
	CWCN	7.68 ± 1.66	0.007	142.20 ± 26.3	0.881

CWOCN, Healthy control without childhood neglect; DWCN, Depression with childhood neglect; DWOCN, Depression without childhood neglect; CWCN, Healthy control with childhood neglect; HPA axis functioning, Cortisol concentrations at 30 minutes after awakening -cortisol concentrations at awakening; p < 0.05 represent significant differences statistically.

ISSN: 1471-244X