Skip to main content

Table 2 Participant baseline characteristics

From: Cognitive behavioural therapy for the treatment of depression in people with multiple sclerosis: a systematic review and meta-analysis

Study Mean age (SD) Sex Mean (SD) MS duration in years MS disease course EDSS/GNDS mean (SD) Depression severity measure mean score (SD)
Larcombe (1984) [48] 42.5 (NR) CBT: F7 M2; Ctrl: F6 M4 NR NR NR BDI. CBT: 27.44 (5.64); Ctrl: 29.00 (8.67)
Mohr (2001) [25] 43.9 (10.0) F46 M17 7.7 (NR) RR or SP EDSS: 2.4 (NR) BDI. CBT: 24.8 (7.1); Ctrl: 23.5 (7.6)
Mohr (2005) [47] CBT: 48.6 (9.6); Ctrl: 47.3 (10.1). CBT: F47 M15; Ctrl: F51 M14 CBT: 11.6 (10.1); Ctrl: 10.9 (10.1) NR GNDS. CBT: 23.9 (5.8); Ctrl 22.9 (6.7) BDI. CBT: 27.00 (7.78); Ctrl: 28.32 (7.91)
Mohr (2000) [45] CBT: 42.6 (12.8); Ctrl: 42.1 (9.4) CBT: F10 M6; Ctrl: F13 M3 CBT: 6.1 (6.6); Ctrl: 6.1 (6.7) CBT: RR16; Ctrl: RR16 GNDS. CBT: 19.0 (9.2); Ctrl: 17.9 (9.2) POMS-DS. CBT: 33.1 (12.4); Ctrl: 27.9 (12.1)
Forman (2010) [43] CBT: 47.3 (10.3); Ctrl: 47.7 (9.8) CBT: F16 M4; Ctrl: F16 M4 CBT: 7.3 (5.4); Ctrl: 12.4 (11.4) CBT: RR13 PP3 SP3 B1; Ctrl: RR13 PP1 SP6 GNDS. CBT: 19.39 (5.55); Ctrl: 25.37 (8.04) HADS-D. CBT: 9.5 (3.3); Ctrl: 8.5 (4.3)
Lincoln (2011) [44] CBT: 44.5 (11.1); Ctrl: 47.5 (10.5) NR CBT: 9.2 (7.8); Ctrl: 10.5 (8.0) CBT: RR55 PP4 SP12 B1; Ctrl: RR48 PP11 SP18 B2 GNDS. CBT: 17.3 (7.8); Ctrl: 16.7 (6.9) BDI. CBT: 23.1 (12.2); Ctrl: 21.9 (8.7)
Cooper (2011) [30] CBT: 48 (7.7); Ctrl: 42 (7.0) CBT: F11 M1; Ctrl: F7 M5 NR CBT: RR7 SP5; Ctrl: RR12 EDSS. CBT: 4.8 (1.7); Ctrl: 3.6 (1.8) BDI. CBT: 21.0 (4.0); Ctrl: 23.3 (5.2)
  1. B: Benign MS disease course; BDI: Beck Depression Inventory; CBT: Cognitive Behavioural Therapy group; Ctrl: Control group; EDSS: Expanded Disability Status Scale; F: Female; GNDS: Guy’s Neurological Disability Scale; HADS-D: Hospital Anxiety and Depression Scale – Depression subscale; M: Male; NR: Not reported; POMS-DS: Profile of Mood States - Depression-Dejection Scale; PP: Primary-progressive MS disease course; RR: Relapsing-remitting MS disease course; SP: Secondary-progressive MS disease course.