Alzheimer’s disease | PPV/NPV at different base rate | ||||||
---|---|---|---|---|---|---|---|
DSR cutoff | Sensitivity | Specificity | 10% | 20%% | 30% | 40% | 50% |
6.50 | 0.992 | 0.907 | 0.54/1.00 | 0.73/1.00 | 0.60/1.00 | 0.64/0.99 | 0.68/0.99 |
7.50 | 0.988 | 0.907 | 0.54/1.00 | 0.73/1.00 | 0.82/0.99 | 0.88/0.99 | 0.91/0.99 |
9.00 | 0.988 | 0.918 | 0.57/1.00 | 0.75/1.00 | 0.84/0.99 | 0.89/0.99 | 0.92/0.99 |
*10.50 | 0.980 | 0.938 | 0.63/1.00 | 0.80/1.00 | 0.87/0.99 | 0.91/0.98 | 0.94/0.98 |
11.50 | 0.972 | 0.938 | 0.63/1.00 | 0.80/1.00 | 0.87/0.99 | 0.91/0.98 | 0.94/0.97 |
12.50 | 0.952 | 0.959 | 0.72/1.00 | 0.85/0.99 | 0.91/0.98 | 0.94/0.97 | 0.96/0.95 |
14.00 | 0.923 | 0.969 | 0.77’0.99 | 0.88/0.98 | 0.93/0.97 | 0.95/0.95 | 0.97/0.93 |
Mild cognitive impairment | PPV/NPV at different base rate | ||||||
DSR cutoff | Sensitivity | Specificity | 10% | 20% | 30% | 40% | 50% |
12.50 | 0.952 | 0.739 | 0.29/0.99 | 0.48/0.98 | 0.60/0.97 | 0.71/0.96 | 0.78/0.94 |
14.00 | 0.923 | 0.761 | 0.30/0.99 | 0.49/0.98 | 0.62/0.96 | 0.72/0.94 | 0.79/0.91 |
*15.50 | 0.899 | 0.799 | 0.33/0.99 | 0.53/0.97 | 0.66/0.95 | 0.75/0.92 | 0.82/0.89 |
16.50 | 0.879 | 0.821 | 0.35/0.98 | 0.55/0.96 | 0.68/0.94 | 0.77/0.91 | 0.83/0.87 |
17.50 | 0.855 | 0.821 | 0.35/0.98 | 0.54/0.96 | 0.67/0.93 | 0.76/0.89 | 0.83/0.85 |
18.50 | 0.819 | 0.836 | 0.36/0.98 | 0.56/0.95 | 0.68/0.92 | 0.77/0.87 | 0.83/0.82 |
19.50 | 0.782 | 0.843 | 0.36/0.97 | 0.55/0.94 | 068/0.90 | 0.77/0.85 | 0.83/0.79 |