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Table 4 Uni- and multivariable associations between cognitive profiles and single MDD (reference) versus comorbid MDD/GAD, and single GAD (reference) versus comorbid MDD/GAD*

From: Disorder-specific cognitive profiles in major depressive disorder and generalized anxiety disorder

 

MDD versus MDD/GAD subscales

GAD versus MDD/GAD subscales

 

Univariable

Multivariable

Univariable

Multivariable

 

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

Depression sensitivity (LEIDS-R)**

    

 Hopelessness/suicidality

0.83 (0.72-0.95)‡

1.03 (0.86-1.25)

0.57 (0.44-0.73)‡

0.70 (0.50-0.97)‡

 Acceptance/coping

0.92 (0.80-1.05)

0.95 (0.82-1.11)

0.84 (0.66-1.07)

0.75 (0.55-1.03)†

 Aggression

0.88 (0.76-1.01)†

1.03 (0.87-1.22)

0.67 (0.51-0.87)‡

0.91 (0.66-1.25)

 Control/perfectionism

0.87 (0.75-1.00)†

1.03 (0.85-1.23)

0.83 (0.66-1.05)

1.21 (0.88-1.66)

 Risk aversion

0.82 (0.71-0.95)‡

1.05 (0.86-1.29)

0.72 (0.58-0.91)‡

1.24 (0.89-1.73)

 Rumination

0.75 (0.64-0.87)‡

0.93 (0.75-1.17)

0.52 (0.41-0.67)‡

0.57 (0.40-0.82)‡

Anxiety sensitivity (ASI)**

    

 Physical concerns

0.83 (0.64-1.10)

1.19 (0.86-1.64)

1.92 (1.26-2.94)‡

4.03 (2.24-7.24)‡

 Social-cognitive concerns

0.63 (0.47-0.85)‡

0.91 (0.62-1.33)

0.59 (0.36-0.96)‡

0.47 (0.23-0.95)‡

Pathological worry (PSWQ)**

0.46 (0.37-0.56)‡

0.45 (0.35-0.57)‡

0.61 (0.44-0.84)‡

0.88 (0.59-1.31)

  1. Note. MDD = major depressive disorder, GAD = generalized anxiety disorder, MDD/GAD = comorbid major depressive disorder and generalized anxiety disorder.
  2. *based on logistic regression analyses corrected for covariates age, sex, education, comorbid social phobia and comorbid panic disorder.
  3. **all items analysed per SD increase.
  4. †p < .10; ‡p < .05.