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Table 2 Treatment recommendation summary

From: Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders

First-line Level 1 or Level 2 evidence plus clinical support for efficacy and safety
Second-line Level 3 evidence or higher plus clinical support for efficacy and safety
Third-line Level 4 evidence or higher plus clinical support for efficacy and safety
Not recommended Level 1 or Level 2 evidence for lack of efficacy