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Table 2 Pharmacological treatments and outcomes favoured by clinicians

From: TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]

Study Favoured regimen Number of Doctors
USA 1999 [4] Haloperidol + lorazepam +/- benztropine 11 (55%)
  Droperidol 4 (20%)
  Benzodizepine (unspecified) alone 3 (15%)
  Droperidol + lorazepam + diphenhydramine 1 (5%)
  Haloperidol + benztropine 1 (5%)
  Use of physical restraints  
  Common 14 (70%)
  Usually not used 6 (30%)
  Route of administration  
  Preferred IM or IV 14 (70%)
  Preferred IM 3 (15%)
  Unknown 3 (15%)
UK 1994 [7] Chlorpromazine 14 (50%)
  Haloperidol 8 (29%)
  Haloperidol + chlorpromazine 2 (7%)
  Droperidol 1 (4%)
  'Neuroleptic' 1 (4%)
  Haloperidol + diazepam 1 (4%)
  Haloeridol + lorazepam 1 (4%)
  Desired end point  
  Sedated but mobile 12 (43%)
  Not sedated but calm 9 (32%)
  Asleep 7 (25%)
  Route of administration  
  Preferred IM 26 (93%)
  Preferred IV 2 (7%)