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Table 4 ZUCLOPENTHIXOL ACETATE versus haloperidol, chlorpromazine or clothiapine – 5 trials, 413 people randomised [11, 6]

From: TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]

Main outcomes Zu. Ac. Control RR (95% CI)
Not sedated by 2 hours 6/20 10/20 0.6 (0.3–1.3)
Needing another injection 12/20 8/20 1.5 (0.8–2.9)
Mental state: no improvement – by 36 hours 11/103 11/85 0.86 (0.4–1.9)
Leaving the study early 6/192 7/166 0.75 (0.3–2.3)