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Table 4 ZUCLOPENTHIXOL ACETATE versus haloperidol, chlorpromazine or clothiapine – 5 trials, 413 people randomised [11, 6]

From: TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]

Main outcomes

Zu. Ac.

Control

RR (95% CI)

Not sedated by 2 hours

6/20

10/20

0.6 (0.3–1.3)

Needing another injection

12/20

8/20

1.5 (0.8–2.9)

Mental state: no improvement – by 36 hours

11/103

11/85

0.86 (0.4–1.9)

Leaving the study early

6/192

7/166

0.75 (0.3–2.3)