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Table 5 Haloperidol versus placebo – 1 trial, 40 participants [15]

From: TREC-Rio trial: a randomised controlled trial for rapid tranquillisation for agitated patients in emergency psychiatric rooms [ISRCTN44153243]

Main outcomes

Hal'dol

Placebo

RR (95% CI)

Not improved by 2 hours

2/29

4/11

0.19 (0.04–0.9)

Needing another injection

Majority in both groups

Mental state: asleep – by 2 hours

1/29

0/11

-

Leaving the study early

0/29

0/11

-

Adverse effects: needing antiparkinsonian medication

6/29

0/11

-