Table 2 Meta-analysis including present and previous association studies between the SIGMAR1 gene and schizophrenia
| Â | Â | Genotype (%) | Â | Allele (%) | Â | |||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Gln/Gln | Gln/Pro | Pro/Pro | p | Gln | Pro | p |
Present study | Control (n = 206) | 92(0.45) | 94(0.45) | 20(0.10) | Â | 278(0.68) | 134(0.32) | Â |
| Â | Schizophrenia (n = 199) | 90(0.45) | 91(0.46) | 18(0.09) | 0.97 | 271(0.68) | 127(0.32) | 0.88 |
Ohmori et al. | Control (n = 140) | 75(0.54) | 55(0.39) | 10(0.07) | Â | 205(0.73) | 75(0.27) | Â |
| Â | Schizophrenia (n = 129) | 67(0.52) | 43(0.33) | 19(0.15) | 0.12 | 177(0.69) | 81(0.31) | 0.25 |
Ishiguro et al. | Control n = 433) | 226(0.52) | 172(0.40) | 35(0.08) | Â | 624(0.72) | 242(0.28) | Â |
| Â | Schizophrenia (n = 308) | 135(0.44) | 144(0.47) | 29(0.09) | 0.08 | 414(0.67) | 202(0.33) | 0.04 |
Total | Control (n = 779) | 393(0.50) | 321(0.41) | 65(0.08) | Â | 1107(0.71) | 451(0.29) | Â |
| Â | Schizophrenia (n = 636) | 292(0.46) | 278(0.44) | 66(0.10) | 0.17 | 862(0.68) | 410(0.32) | 0.06 |