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Table 3 Comparison of hormone parameters:AUC for the first (23.00 h – 3.00 h) and second (3.00 h – 7.00 h) half of the night.

From: The Renin-Angiotensin-Aldosterone system in patients with depression compared to controls – a sleep endocrine study

 

depressed patients AUC

controls AUC

significance

1. half

   

ACTH (pg/ml × min)

3180 ± 1608

3193 ± 1074

n.s.

cortisol (ng/ml × min)

23690 ± 15330

11002 ± 4945

(n.s) p = 0.06

renin (pg/ml × min)

1656 ± 1000

1359 ± 249

n.s.

aldosterone (pg/ml × min)

9370 ± 5404

2914 ± 2932

p = 0.022

2. half

   

ACTH (pg/ml × min)

5601 ± 1741

6807 ± 2452

n.s.

cortisol (ng/ml × min)

45682 ± 17309

33395 ± 8991

n.s.

renin (pg/ml × min)

1588 ± 919

1504 ± 433

n.s.

aldosterone (pg/ml × min)

16075 ± 5908

6799 ± 4469

p = 0.009