Figure 1
The primary portion of brain reward circuitry appears to be a subset of dopaminergic projections originating in the ventral tegmental area (VTA) and terminating in the nucleus accumbens (NA). VTA is modulated by GABAergic inputs. GABAB receptors inhibit VTA cell bodies, i.e., when stimulated, hyperpolarize the membrane potential and decrease firing rates of VTA neurons.
