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Table 1 Haematological indices, vitamin B12 and folate, and six-month treatment outcome in major depressive disorder (n = 115)

From: High vitamin B12 level and good treatment outcome may be associated in major depressive disorder

  Nonresponse (n = 40) Partial response (n = 34) Full response (n = 41)
  Mean (SD) Mean (SD) Mean (SD)
Haemoglobin (g/l) 141.7 (10.1) 141.1 (13.3) 139.1 (14.8)
Mean corpuscular volume (fl) 92.5 (6.0) 90.4 (5.8) 89.5 (6.6)
Red blood cell count (cell12/l) 4.51 (0.46) 4.57 (0.39) 4.56 (0.42)
Hematocrit (%) 41.6 (3.1) 41.2 (3.7) 40.8 (4.0)
Vitamin B12 at baseline (pmol/l)1 347.2 (103.4) 396.0 (108.4) 439.1 (115.6)
Vitamin B12 on follow-up (pmol/l)2 280.4 (93.3) 316.2 (98.2) 338.8 (87.5)
Folate at baseline (nmol/l) 409.7 (126.0) 431.5 (114.8) 446.8 (244.8)
HDRS score at baseline3 16.8 (7.2) 22.3 (5.6) 17.8 (5.4)
HDRS score on follow-up4 17.6 (4.9) 13.8 (3.7) 4.6 (3.2)
  1. ANOVA: 1 F = 7.17, p = 0.001. 2 F = 4.07, p = 0.02. 3 F = 8.10, p = 0.01. 4 F = 112.58, p < 0.001.