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Table 1 Haematological indices, vitamin B12 and folate, and six-month treatment outcome in major depressive disorder (n = 115)

From: High vitamin B12 level and good treatment outcome may be associated in major depressive disorder

 

Nonresponse (n = 40)

Partial response (n = 34)

Full response (n = 41)

 

Mean (SD)

Mean (SD)

Mean (SD)

Haemoglobin (g/l)

141.7 (10.1)

141.1 (13.3)

139.1 (14.8)

Mean corpuscular volume (fl)

92.5 (6.0)

90.4 (5.8)

89.5 (6.6)

Red blood cell count (cell12/l)

4.51 (0.46)

4.57 (0.39)

4.56 (0.42)

Hematocrit (%)

41.6 (3.1)

41.2 (3.7)

40.8 (4.0)

Vitamin B12 at baseline (pmol/l)1

347.2 (103.4)

396.0 (108.4)

439.1 (115.6)

Vitamin B12 on follow-up (pmol/l)2

280.4 (93.3)

316.2 (98.2)

338.8 (87.5)

Folate at baseline (nmol/l)

409.7 (126.0)

431.5 (114.8)

446.8 (244.8)

HDRS score at baseline3

16.8 (7.2)

22.3 (5.6)

17.8 (5.4)

HDRS score on follow-up4

17.6 (4.9)

13.8 (3.7)

4.6 (3.2)

  1. ANOVA: 1 F = 7.17, p = 0.001. 2 F = 4.07, p = 0.02. 3 F = 8.10, p = 0.01. 4 F = 112.58, p < 0.001.