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Table 2 Extrapyramidal symptoms based on Extrapyramidal Symptoms Rating Scale

From: Ritanserin as an adjunct to lithium and haloperidol for the treatment of medication-naive patients with acute mania: a double blind and placebo controlled trial

 

Mean ± SEM Lithium + Haloperidol+ Ritanserin

Mean ± SEM Lithium + Haloperidol+ Placebo

P

Day 0

1.70 ± 0.17

1.80 ± 0.44

0.83

Day 3

2.30 ± 0.44

2.35 ± 0.42

0.93

Day 7

2.30 ± 0.20

2.80 ± 0.33

0.21

Day 14

2.65 ± 0.28

3.05 ± 0.40

0.42

Day 21

2.00 ± 0.24

2.85 ± 0.37

0.18

Day 28

1.95 ± 0.22

3.00 ± 0.49

0.059

Day 42

1.50 ± 0.17

3.00 ± 0.39

0.001***