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Table 1 Summary of studies included in the comparisons between MMRM and LOCF_ANCOVA

From: The efficacy of duloxetine: A comprehensive summary of results from MMRM and LOCF_ANCOVA in eight clinical trials

Study Treatment Duration Drug Number of Patients Drug Dose & Design
1 9 weeks Placebo 122 -
   Duloxetine 123 60 mg/d (QD)
2 9 weeks Placebo 139 -
   Duloxetine 128 60 mg/d (QD)
3 8 weeks Placebo 70 -
   Duloxetine 70 40–120 mg/d (20 mg-60 mg BID)
   Fluoxetine 33 20 mg/d (QD)
4 8 weeks Placebo 75 -
   Duloxetine 82 40–120 mg/d (20 mg-60 mg BID)
   Fluoxetine 37 20 mg/d (QD)
5 8 weeks Placebo 90 -
   Duloxetine 91 40 mg/d (20 mg BID)
   Duloxetine 84 80 mg/d (40 mg BID)
   Paroxetine 89 20 mg/d (QD)
6 8 weeks Placebo 89 -
   Duloxetine 86 40 mg/d (20 mg BID)
   Duloxetine 91 80 mg/d (40 mg BID)
   Paroxetine 87 20 mg/d (QD)
7 8 weeks Placebo 93 -
   Duloxetine 95 80 mg/d (40 mg BID)
   Duloxetine 93 120 mg/d (60 mg BID)
   Paroxetine 86 20 mg/d (QD)
8 8 weeks Placebo 99 -
   Duloxetine 93 80 mg/d (40 mg BID)
   Duloxetine 103 120 mg/d (60 mg BID)
   Paroxetine 97 20 mg/d (QD)