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Table 1 Clinical parameters for all the groups (mean ± SD), (paired t-test).

From: Single photon emission computed tomography (SPECT) of anxiety disorders before and after treatment with citalopram

  

Baseline

Endpoint

p

OCD (n = 11)

YBOCS

26.6 ± 4.7

23.7 ± 5.8

0.001

 

MADRS

13.64 ± 9.6

9.9 ± 6.4

0.119

 

CGI-severity

4.7 ± 0.647

4.18 ± 1.1

0.025

 

CGI-improvement

 

3.1 ± 0.7

 

SAD (n = 15)

LSAS

79.2 ± 30.2

63.1 ± 28.5

0.003

 

MADRS

15 ± 4.9

9.1 ± 5.9

0.004

 

CGI-severity

4.6 ± 0.8

3.3 ± 1.1

0.001

 

CGI-improvement

 

2.7 ± 1.2

 

PTSD (n = 11)

CAPS

78.1 ± 16.9

45.5 ± 23.9

<0.01

 

MADRS

25 ± 6.7

15.9 ± 8.0

<0.01

 

CGI -severity

4.5 ± 0.5

2.5 ± 0.7

<0.01

 

CGI-improvement

 

1.9 ± 0.7

 
  1. YBOCS, Yale Brow Obsessive-compulsive scale; MADRS, Montgomery Asberg Depression Rating scale; CGI-s, Clinical global impressions severity; CGI-I, Clinical global impressions – improvement; LSAS, Liebowitz Social Anxiety Scale; CAPS, Clinician Administered PTSD scale.