Table 4 Mean changes from baseline to last observation by gender in melancholic patients
| Â | Gender | Mean Change (SD) | p-valuea | p-valueb | |
|---|---|---|---|---|---|
| Â | Â | Duloxetine | Placebo | Â | Â |
HAMD 17 Total Score | Male (n = 386) | -7.99 (7.04) | -5.95 (7.13) | .003 | .932 |
| Â | Female (n = 863) | -9.42 (7.46) | -6.83 (7.29) | <.001 | Â |
CGI-Severity | Male (n = 386) | -1.41 (1.28) | -0.97 (1.22) | .001 | .668 |
| Â | Female (n = 865) | -1.57 (1.24) | -1.17 (1.20) | <.001 | Â |
| Â | Mean (SD) | ||||
PGI-Improvement †| Male (n = 385) | 2.80 (1.27) | 3.13 (1.23) | .009 | .877 |
| Â | Female (n = 864) | 2.61 (1.26) | 3.04 (1.29) | <.001 | Â |