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Table 2 Effects of treatment on PANSS factors, depressive symptoms and the clinical global impression.

From: The effects of amisulpride on five dimensions of psychopathology in patients with schizophrenia: a prospective open- label study

 

Baseline

Week 2

Week 4

Week 12

Statistics

p value

PANSS Factors

      

Positive

25.7 (8.6)

18.2 (6.6)

14.7 (7.1)

13 (6.6)

F(3,77) = 33

<0.001

Negative

26.8 (8.3)

19.3 (7.1)

16.3 (7.3)

13.8 (6.4)

F(3,77) = 41.1

<0.001

Cognitive

19.8 (6.2)

14 (5.2)

12.8 (5.2)

11.2 (5)

F(3,77) = 24.4

<0.001

Excitement

9.4 (4.1)

6.1 (2.8)

5.6 (3)

5.2 (2)

F(3,77) = 17.6

<0.001

Depression/Anxiety

9.7 (4.3)

7.3 (2.9)

6.4 (3)

5.4 (2.6)

F(3,77) = 21.6

<0.001

Total Score

91.5 (23.8)

78.4(16.9)

56 (21.9)

48.8 (20.1)

F(3,77) = 43.6

<0.001

CDSS

3.9 (4.9)

2.4 (3)

1.7 (2.9)

1 (2.7)

F(3,77) = 9.6

<0.001

CGI

      

Severity

4.7 (1.1)

3.4 (1.1)

2.8 (1.2)

2.3 (1.4)

F(3,77) = 54.2

<0.001

Improvement

 

2.5 (0.9)

2.2 (1)

2.3 (1.4)

F(2,78) = 2.1

0.12

  1. Mean (S.D.)
  2. PANSS, Positive and negative syndrome scale
  3. CDSS, Total score of the Calgary depression scale for schizophrenia
  4. CGI, Clinical global impression scale