Skip to main content

Table 3 Mean change from baseline to endpoint in secondary efficacy measures

From: The effects of amisulpride on five dimensions of psychopathology in patients with schizophrenia: a prospective open- label study

PANSS Factors

Predominantly Negative (n = 30)

Predominantly Positive (n = 40)

Statistic* Between Groups

Statistic* During the Follow-up

 

Mean

SD

Mean

SD

  

Positive

      

Baseline

19.5

6.8

30.4

6.8

F = 1.09, df 1, p = 0.29

F = 79.58, df 1, p < 0.001

Mean Change

-7.2

10.1

-16.7

9.6

  

Negative

      

Baseline

30.8

8.6

23.8

6.8

F = 0.16, df 1, p = 0.68

F = 80.18, df 1, p < 0.001

Mean Change

-16.3

11.2

-10.5

8.1

  

Cognitive

      

Baseline

18.5

6.7

20.7

5.7

F = 0.01, df 1, p = 0.91

F = 111.29, df 1, p < 0.001

Mean Change

-7.1

9.4

-9.6

7.3

  

Excitement

      

Baseline

8.0

4.0

10.4

3.9

F = 2.63, df 1, p = 0.10

F = 304.76, df 1, p < 0.001

Mean Change

-3.1

4.7

-4.9

4.7

  

Depression-Anxiety

      

Baseline

8.9

4.2

10.3

4.2

F = 0.16, df 1, p = 0.68

F = 171.77, df 1, p < 0.001

Mean Change

-3.6

4.9

-4.7

5.1

  

Total score

      

Baseline

85.8

25.1

95.8

22.1

F = 0.05, df 1, p = 0.82

F = 94.80, df 1, p < 0.001

Mean Change

-37.4

35.3

-46.6

28.4

  
  1. * Based on analysis of covariance adjusted for baseline score.