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Table 2 Daily Dose (mg/day) of Index Atypical Antipsychotic: During the 1-Year Post Initiation, at Initiation, and at Endpoint

From: Antipsychotic monotherapy and polypharmacy in the naturalistic treatment of schizophrenia with atypical antipsychotics

Group/Time

Mean (SD)

Median

Min/Max

Mean Mono/Poly*

Olanzapine

    

   1-Year

13.9 (7.4)

10.0

2.5/40

15.1/13.5

   Initiation

10.0 (6.1)

10.0

2.5 / 40

10.7 / 9.5

   Endpoint

14.2 (8.4)

10.0

2.5 / 50

13.9 / 14.5

Quetiapine

    

   1-Year

330 (214)

295

25/850

305/334

   Initiation

164.2 (151)

100

12.5 / 800

223 / 138

   Endpoint

341 (277)

300

25 / 1300

369 / 330

Risperidone

    

   1-Year

4.2 (2.3)

3.9

0.28/12.9

4.7/3.9

   Initiation

2.7 (2.0)

2.0

0.25 / 12

3.2 / 2.4

   Endpoint

4.3 (2.7)

4.0

0.25 / 16

4.5 / 4.1

  1. * Mean Mono/Poly indicates the mean dose (mg/day) for patients while on antipsychotic monotherapy, and while on antipsychotic polypharmacy