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Table 1 Gender differences at baseline*

From: Acute weight gain, gender, and therapeutic response to antipsychotics in the treatment of patients with schizophrenia

  All patients Women Men  
Characteristic N = 1996 N = 700 N = 1296 P
Demographics     
   Age 38.6 (11.4) 40.9 (12.8) 37.3 (10.4) <0.001
   Race     0.013
Caucasian 1600 (80.2%) 587 (83.9%) 1013 (78.2%) 0.002
African descent 220 (11.0%) 67 (9.6%) 153 (11.8%) 0.128
Hispanic 83 (4.2%) 19 (2.7%) 64 (4.9%) 0.018
Other 93 (4.7%) 27 (3.9%) 66 (5.1%) 0.211
   Diagnosis     <0.001
Schizophrenia 1658 (83.1%) 526 (75.1%) 1132 (87.3%) <0.001
Schizoaffective disorder 300 (15.0%) 157 (22.4%) 143 (11.0%) <0.001
Schizophreniform disorder 38 (1.9%) 17 (2.4%) 21 (1.6%) 0.207
Core schizophrenia symptoms     
   BPRS total 33.4 (10.7) 33.5 (11.2) 33.3 (10.5) 0.660
   BPRS positive 10.3 (4.1) 10.0 (4.1) 10.5 (4.0) 0.017
   BPRS negative 6.7 (3.3) 6.7 (3.4) 6.7 (3.3) 0.791
Depressive symptoms     
   MADRS 16.6 (8.8) 17.3 (9.3) 16.3 (8.5) 0.031
   BPRS anxiety and depression 7.5 (3.8) 8.0 (3.9) 7.3 (3.8) <0.001
Functional status     
   SF-36 physical component 43.6 (13.0) 41.4 (14.0) 44.5 (12.5) 0.004
   SF-36 mental component 34.6 (12.4) 34.6 (12.9) 34.6 (12.2) 0.958
Weight     
   Weight, kg 76.8 (17.1) 70.2 (16.4) 80.4 (16.3) <0.001
   BMI 26.0 (5.2) 26.5 (5.8) 25.8 (4.9) 0.007
   BMI level     <0.001
Underweight to average (BMI < 25) 930 (48.9%) 319 (47.6%) 611 (49.6%) 0.418
Overweight (BMI ≥ 25 and < 30) 609 (32.0%) 191 (28.5%) 418 (33.9%) 0.016
Obese (BMI ≥ 30) 364 (19.1%) 160 (23.9%) 204 (16.5%) <0.001
  1. * Data are presented as Mean (SD) or N (%).
  2. P-values refer to differences between women and men.