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Table 3 Conditional probability of response given different amounts of weight gain for all patients and by medication

From: Acute weight gain, gender, and therapeutic response to antipsychotics in the treatment of patients with schizophrenia

 

Olanzapinea

Haloperidolb

 

N = 1283

N = 622

Weight change

Did not respond

Respondedc

P(R| W)

Did not respond

Respondedc

P(R| W)

 

N

%

N

%

 

N

%

N

%

 

Lost weight (< 0%)

210

16.4%

187

14.6%

.47

176

28.3%

166

26.7%

.49

Gained 0 to < 3%

118

9.2%

234

18.3%

.67

88

14.2%

83

13.3%

.49

Gained 3 to < 7%

111

8.7%

248

19.3%

.69

39

6.3%

51

8.2%

.57

Gained ≥ 7%

43

3.4%

132

10.3%

.75

5

0.8%

14

2.3%

.74

  1. Note. Response was defined as a greater than 20% decrease in BPRS Core Symptoms
  2. a Mantel-Haenszel test of linear by linear association, χ 2(1, N = 1283) = 52.3, p < 0.001.
  3. b Mantel-Haenszel test of linear by linear association, χ 2(1, N = 622) = 4.1, p = 0.044.
  4. cProbability of response given level of weight change.
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BMC Psychiatry

ISSN: 1471-244X

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