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Table 2 Allele and genotype distribution of polymorphisms spanning the FKBP5 locus

From: Is FKBP5 a genetic marker of affective psychosis? A case control study and analysis of disease related traits

 

Controls

Cases

 

Allele

Genotype

Allele

 

Genotype

 
 

1 (%)

2 (%)

11

12

22

HWE

1 (%)

2 (%)

P-value+

11

12

22

HWE

P-value*

rs4713916 A/G

110 (29.3)

266 (70.7)

18

74

96

0.50

160 (32.3)

336 (67.7)

0.38

19

122

107

0.048

0.12

rs1360780 C/T

262 (69.7)

114 (30.3)

94

74

20

0.35

338 (68.2)

158 (31.8)

0.66

114

110

24

0.73

0.86

rs3800373 T/G

275 (73.1)

101 (26.9)

102

71

15

0.60

344 (69.4)

152 (30.6)

0.23

115

114

19

0.20

0.87

  1. HWE: P-value of Weir's test for Hardy-Weinberg Equilibrium
  2. +: P-value of Fisher's exact test for comparison of allele frequencies between cases and controls
  3. *: P-value of Armitage's trend test for comparison of genotype frequencies between cases and controls
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BMC Psychiatry

ISSN: 1471-244X

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