Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia

BMC Psychiatry

Table 3 Differences between atypical and typical antipsychotics of high, medium, and low potency on time to all-cause medication discontinuation

	CLZ, OLZ, RIS, QUE, ZIP (combined)	CLZ	OLZ	RIS	QUE	ZIP
High-potency typicals
Log-rank test	**	**	**	**	**	NS
Cox PH model	**	**	**	**	*	NS
Propensity score bootstrap	**	**	**	**	*	NS
Medium-potency typicals
Log-rank test	**	**	**	*	NS	NS
Cox PH model	**	**	**	*	NS	NS
Propensity score bootstrap	**	**	**	*	NS	NS
Low-potency typicals
Log-rank test	**	**	**	NS	NS	NS
Cox PH model	*	**	*	*	NS	NS
Propensity score bootstrap	**	**	**	*	NS	NS
All typicals
Log-rank test	**	**	**	**	**	NS
Cox PH model	**	**	**	**	NS	NS
Propensity score bootstrap	**	**	**	**	NS	NS

Abbreviations: CLZ, clozapine; OLZ, olanzapine; RIS, risperidone; QUE, quetiapine; ZIP, ziprasidone; NS, not significant *Significant at p < 0.05 level **Significant at p ≤ 0.01 level

ISSN: 1471-244X