| Methadone substituted opiate addicts | Control subjects | ||||
---|---|---|---|---|---|---|
 | whole group | without concomitant non-opioid drug use | with concomitant non-opioid drug use | whole group | without nicotine consumption | with nicotine consumption |
 | mean (sd) | mean (sd) | mean (sd) | mean (sd) | mean (sd) | mean (sd) |
P300 Amplitude (μV) |  |  |  |  |  |  |
Fz | 23.3 (14.3) | 22.5 (14.1) | 23.8 (15.1) | 25.1 (13.3) | 30.9 (10.9) | 18.3 (12.9) |
Cz | 27.6 (14.6) | 26.5 (15.5) | 28.3 (14.2) | 26.9 (15.5) | 34.2 (12.8) | 18.4 (14.1) |
Pz | 33.4 (12.3) | 32.9 (14.4) | 33.7 (11.1) | 31.7 (14.5) | 37.7 (12.7) | 24.8 (13.5) |
P300 Latency (ms) | Â | Â | Â | Â | Â | Â |
Fz | 327 (36) | 337 (39) | 322 (34) | 335 (20) | 331 (18) | 340 (21) |
Cz | 333 (43) | 339 (42) | 330 (45) | 335 (23) | 332 (24) | 339 (22) |
Pz | 339 (40) | 348 (33) | 333 (44) | 339 (29) | 339 (26) | 338 (32) |
Reaction Time (RT) | Â | Â | Â | Â | Â | Â |
RT (ms) between subjects | 409 (97) | 442 (87) | 390 (98) | 422 (101) | 397 (93) | 450 (104) |
Standard deviation of RT within subjects (ms) | 76 (29) | 87 (34) | 70 (24) | 73 (29) | 64 (17) | 83 (34) |