Skip to main content

Table 1 Mean cognitive test scores at baseline (week 0) and after 12, 26, 52 and 78 weeks of cholinesterase inhibitor treatment for all patients and the sub-sample who had NARTIQ scores.

From: Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: a longitudinal study in a treated cohort

Test (week)

N All patients

Mean score

Standard deviation

N Patients with NARTIQ scores

Mean score

Standard deviation

MMSE(0)

626

19.3

5.8

346

20.7

4.9

HVLT(0)

601

9.2

4.9

342

10.0

5.0

VF-Cat(0)

604

7.8

4.3

344

8.7

4.4

VF-Lex(0)

604

22.0

13.1

342

24.8

13.5

PAL(0)

461

4.3

1.8

298

4.5

1.8

DMTS(0)

447

11.1

3.1

290

11.5

2.8

MMSE(12)

143

19.5

5.5

101

20.3

5.2

HVLT(12)

84

9.7

5.6

67

10.2

5.7

VF-Cat(12)

82

8.5

5.0

66

9.0

5.3

VF-Lex(12)

82

24.3

14.9

66

25.7

15.2

PAL(12)

70

4.2

1.7

59

4.1

1.7

DMTS(12)

71

10.8

2.9

58

11.0

2.9

MMSE(26)

259

19.0

5.6

162

19.7

5.5

HVLT(26)

250

9.5

4.6

157

9.9

4.9

VF-Cat(26)

248

7.6

4.2

158

8.1

4.5

VF-Lex(26)

248

23.2

12.5

158

24.8

12.5

PAL(26)

170

4.5

1.8

124

4.4

1.7

DMTS(26)

183

11.1

3.1

127

11.2

3.0

MMSE(52)

96

18.6

5.4

75

19.0

5.3

HVLT(52)

87

9.2

5.7

69

9.3

5.8

VF-Cat(52)

87

6.9

4.5

68

7.0

4.7

VF-Lex(52)

87

23.5

13.9

68

25.0

14.0

PAL(52)

76

4.4

1.6

62

4.3

1.6

DMTS(52)

75

10.9

2.8

58

10.7

2.8

MMSE(78)

43

19.2

5.5

33

19.6

5.7

HVLT(78)

38

9.9

6.2

20

10.3

6.3

VF-Cat(78)

39

7.6

4.7

31

7.9

5.0

VF-Lex(78)

39

25.1

13.6

31

26.9

13.5

PAL(78)

29

4.3

1.8

23

4.3

1.8

DMTS(78)

33

10.6

3.4

25

10.7

3.4

  1. MMSE – Mini-Mental State Examination; HVLT – Hopkins Verbal Learning Test total score over six trials; V-Cat – Categorical Verbal Fluency; V-Lex – Lexical Verbal Fluency; PAL – Paired Associates Learning from CANTAB battery; DMTS – Delayed Matching to Sample stages from the CANTAB battery.