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Table 4 Reason for Sertindole Discontinuation during Study Follow-up (682 patients), with type of previously taken treatment

From: The Sertindole Safety Survey: A retrospective analysis under a named patient use programme in Europe

 

Total N (%)

Reason for Stopping

Beforea

Afterb

Sertindole suspension and Named Patient Use restrictions

176 (35.3%)

49 (26.8%)

Typical antipsychotic(s)c

50 (25.1%)

28 (31.5%)

At least one atypical antipsychoticd

49 (31.6%)

15 (20.8%)

Patient desire to stop

127 (25.5%)

50 (27.3%)

Typical antipsychotic(s)c

71 (35.7%)

26 (29.2%)

At least one atypical antipsychoticd

39 (25.2%)

18 (25.0%)

Lack of efficacy

64 (12.8%)

39 (21.3%)

Typical antipsychotic(s)c

28 (14.1%)

17 (19.1%)

At least one atypical antipsychoticd

23 (14.8%)

19 (26.4%)

Adverse Event(s)

58 (11.6%)

19 (10.4%)

Typical antipsychotic(s)c

26 (13.1%)

10 (11.2%)

At least one atypical antipsychoticd

20 (12.9%)

9 (12.5%)

Other reasons

74 (14.8%)

26 (14.2%)

Typical antipsychotic(s)c

24 (12.1%)

8 (9.0%) 11

At least one atypical antipsychoticd

24 (15.5%)

(15.3%)

Total

499 (100.0%)

183 (100.0%)

  1. a For 2 patients, reason for stopping sertindole treatment was missing.
  2. b For 1 patient, reason for stopping sertindole treatment was missing.
  3. c For 129 patients, the name of the antipsychotic given before sertindole treatment was missing and 48 patients had no antipsychotic treatment before sertindole.
  4. d For 8 patients, the name of the antipsychotic given before sertindole treatment was missing and 25 patients had no antipsychotic treatment before sertindole.