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Table 2 Types of intervention trial and year of publication

From: Randomised trials relevant to mental health conducted in low and middle-income countries: a survey

Type of trial 1991 1995 2000 Total
  n = 25 (%) n = 45 (%) n = 107 (%) n = 177 (%)
Drug vs drug 13 (52) 20 (44) 56 (52) 89 (50)
Drug vs non-active (eg placebo) 4 (16) 9 (20) 20 (19) 33 (19)
Drug vs psychosocial - - 7 (7) 7 (4)
Drug vs biological non-drug (eg ECT) 2 (8) 2 (4) 2 (2) 6 (3)
Drug vs mixed (eg placebo AND psychotherapy) - - 1 (<1) 1 (<1)
Drug dose finding 1 (4) 2 (4) 1 (<1) 4 (2)
Total trials involving drugs 20 (80) 33 (73) 87 (81) 140 (80)
Biological non-drug vs biological non-drug 1 (4) 2 (4) 3 (3) 6 (3)
Psychosocial vs psychosocial 4 (16) 4 (9) 5 (5) 13 (7)
Psychosocial vs non-active   3 (7) 8 (7) 11 (6)
Biological non-drug vs non-active   1 (2) 3 (5) 4 (2)
  1. ECT = electroconvulsive therapy