Figure 1

Weight change (kg) and BMI change (kg/m ² ) from baseline to 30-week endpoint in Studies 1 and 2. For Study 1 (N = 669), the mean (standard deviation [SD]) weight change was 5.4 kg (6.9); for Study 2 (N = 102), it was 5.2 kg (6.6). Data were grouped into intervals of 4 kg with midpoints of each interval shown along horizontal axes. The height of each bar corresponds to the proportion of patients whose weight change falls within that range. For Study 1 (N = 661), the mean (SD) BMI change was 1.9 (2/4) kg/m²; for Study 2, (N = 101), the mean (SD) BMI change was 1.8 (2.3) kg/m². Data were grouped in intervals of 1 kg/m² with midpoints of each interval shown along the horizontal axes. The height of each bar corresponds to the proportion of patients whose BMI change falls within that range.