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Table 1 Patient Characteristics at Baseline

From: Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis

 

Nizatidine

Study

(n = 68)

Sibutramine Study

(n = 42)

Amantadine Study

(n = 48)

Total

(N = 158)

Age, years; mean (SD)

43.5 (10.2)

38.7 (11.6)

40.6 (12.0)

41.3 (11.3)

Weight, kg; mean (SD)

85.1 (12.2)

99.8 (19.7)

95.1 (18.9)

92.1 (17.7)

BMI, kg/m2; mean (SD)

30.1 (3.8)

35.0 (5.7)

32.3 (5.4)

32.1 (5.2)

Age at disease onset, years; mean (SD)

25.5 (7.5)

23.6 (9.8)

24.6 (10.6)

24.7 (9.1)

BPRS; mean (SD)

21.0 (14.1)a

8.3 (6.8)

11.6 (8.3)

14.6 (12.1)

Caucasian race, %

67.6

78.6

81.3

74.7

Gender, % males

60.3

35.7

47.9

50.0

EBA Total; mean (SD)

11.4 (4.8)b

19.2 (6.2)

19.7 (7.9)

16.0 (7.4)

VAS (hunger); mean (SD)

4.2 (2.2)c

5.7 (2.3)

6.1 (2.3)

5.2 (2.4)

VAS (interest in food); mean (SD)

4.8 (2.7)c

5.4 (2.5)

6.4 (2.9)

5.4 (2.8)

VAS (appetite); mean (SD)

4.9 (2.4)c

5.9 (2.6)

6.7 (2.6)

5.7 (2.6)

Eating Inventory (cognitive restraint); mean (SD)

7.1 (4.1)b

8.1 (3.1)

7.4 (3.9)

7.5 (3.8)

Eating Inventory (disinhibition); mean (SD)

5.0 (3.0)b

8.2 (3.8)

7.4 (3.3)

6.6 (3.6)

Eating Inventory (hunger); mean (SD)

5.2 (2.9)b

8.4 (3.1)

8.3 (3.3)

7.0 (3.4)

  1. Abbreviations: BMI = body mass index; BPRS = Brief Psychiatric Rating Scale; EBA = Eating Behaviors Assessment: total of 9 items; each item is rated from 0 (not at all) to 4 (extremely); EI = Eating Inventory; SD = standard deviation; VAS = Visual Analog Scale: measurements are points on a scale from 0 (not at all) to 10 (extremely).
  2. an = 65
  3. bn = 67
  4. cn = 66