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Table 1 Patient Characteristics at Baseline

From: Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis

  Nizatidine
Study
(n = 68)
Sibutramine Study
(n = 42)
Amantadine Study
(n = 48)
Total
(N = 158)
Age, years; mean (SD) 43.5 (10.2) 38.7 (11.6) 40.6 (12.0) 41.3 (11.3)
Weight, kg; mean (SD) 85.1 (12.2) 99.8 (19.7) 95.1 (18.9) 92.1 (17.7)
BMI, kg/m2; mean (SD) 30.1 (3.8) 35.0 (5.7) 32.3 (5.4) 32.1 (5.2)
Age at disease onset, years; mean (SD) 25.5 (7.5) 23.6 (9.8) 24.6 (10.6) 24.7 (9.1)
BPRS; mean (SD) 21.0 (14.1)a 8.3 (6.8) 11.6 (8.3) 14.6 (12.1)
Caucasian race, % 67.6 78.6 81.3 74.7
Gender, % males 60.3 35.7 47.9 50.0
EBA Total; mean (SD) 11.4 (4.8)b 19.2 (6.2) 19.7 (7.9) 16.0 (7.4)
VAS (hunger); mean (SD) 4.2 (2.2)c 5.7 (2.3) 6.1 (2.3) 5.2 (2.4)
VAS (interest in food); mean (SD) 4.8 (2.7)c 5.4 (2.5) 6.4 (2.9) 5.4 (2.8)
VAS (appetite); mean (SD) 4.9 (2.4)c 5.9 (2.6) 6.7 (2.6) 5.7 (2.6)
Eating Inventory (cognitive restraint); mean (SD) 7.1 (4.1)b 8.1 (3.1) 7.4 (3.9) 7.5 (3.8)
Eating Inventory (disinhibition); mean (SD) 5.0 (3.0)b 8.2 (3.8) 7.4 (3.3) 6.6 (3.6)
Eating Inventory (hunger); mean (SD) 5.2 (2.9)b 8.4 (3.1) 8.3 (3.3) 7.0 (3.4)
  1. Abbreviations: BMI = body mass index; BPRS = Brief Psychiatric Rating Scale; EBA = Eating Behaviors Assessment: total of 9 items; each item is rated from 0 (not at all) to 4 (extremely); EI = Eating Inventory; SD = standard deviation; VAS = Visual Analog Scale: measurements are points on a scale from 0 (not at all) to 10 (extremely).
  2. an = 65
  3. bn = 67
  4. cn = 66