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Table 4 Significant Predictors of Weight Loss

From: Predictors and correlates for weight changes in patients co-treated with olanzapine and weight mitigating agents; a post-hoc analysis

Variable HR 95% CI Interpretation
Baseline BMI 1.09b 1.03–1.15 Patients with higher baseline BMI were more likely to lose weight, and patients with lower baseline BMI were less likely to lose weight
Baseline VAS2 (interest in food) 0.81c 0.73–0.91 Patients who had less interest in food were more likely to lose weight and patients who had more interest in food were less likely to lose weight
Change from baseline in appetite (EBA-2) 0.65b 0.48–0.86 Patients experiencing a decrease in appetite were more likely to lose weight and patients experiencing an increase in appetite were less likely to lose weight
Change from baseline in cravings for sweets or other carbohydrates (EBA-3) 0.75a 0.59–0.94 Patients experiencing decreased craving for carbohydrates were more likely to lose weight and patients experiencing increased craving for carbohydrates were less likely to lose weight
Change from baseline in hunger (VAS1) 0.87a 0.76–0.99 Patients experiencing a decrease in hunger were more likely to lose weight and patients experiencing an increase in hunger were less likely to lose weight
  1. Abbreviations: BMI = body mass index; CI = confidence interval; EBA = Eating Behaviors Assessment; HR = hazard ratio; VAS = Visual Analog Scale.
  2. Pooled analysis across all 3 studies
  3. HR was adjusted for study effect and other variables included in the model
  4. ap < .05, bp < .01, cp < .001