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Table 1 Antipsychotic equivalent doses and Defined Daily Doses of common antipsychotics.

From: Treatment of schizophrenia with antipsychotics in Norwegian emergency wards, a cross-sectional national study

FGA     
Drug Potency Ratio Antipsychotic equivalent doses. DDD5 (mg) Adm-route
Low-potency     
Chlorpromazine (Largactil®) 1.0 300.0 300.0 O
Klorprotixene (Truxal ®) 2.0 150.02 300.0 O
Levomepromazine (Nozinan®) 1.0 300.05 300.0 O
Thioridazine (Melleril®) 1.0 300.01 300.0 O
Medium potency     
Dixyrazine (Esucos®) 6.0 50.05 50.0 O
Perphenazine (Trilafon®) 12.5 24.01 30.0 O
Perphenazine decanoate (Trilafon depot®) 53.0 5.75 7.0 P
Prochlorperazine (Stemetil®) 6.7 45.01 100.0 O
Zuclopenthixol (Cisordinol®) 4.0 75.01 30.0 O
Zuclopenthixol decanoate (Cisordinol Depot®) 7.0 42.01 15.0 P
High-potency     
Flupenthixol (Fluanxol®) 50.0 6.01 6.0 O
Flupenthixol decanoate (Fluanxol depot®) 70.0 4.21 4 4.0 P
Haloperidol (Haldol®) 33.0 9.01 8.0 O
Haloperidol decanoate (Haldol depot®) 50.0 6.01 4 3.3 P
SGA     
Amisulpride (Solian®) 1.0 300.01 400.0 O
Aripiprazole (Abilify®) 13.3 22.53 15.0 O
Clozapine (Leponex®, Clozapine®) 1.0 300.01 300.0 O
Olanzapine (Zyprexa®) 20.0 15.03 10.0 O
Quetiapine (Seroquel®) 1.3 225.03 400.0 O
Risperidone (Risperdal®) 66.0 4.51 5.0 O
Risperidone long-acting injection (Risperdal Consta®) 100.0 3.06 1.8 P
Sertindole (Serdolect®) 18.8 16.05 16.0 O
Ziprazidone (Zeldox®) 1.6 180.03 80.0 O
  1. 1Bazire, S. (2005) Psychotropic Drug Directory 2005. [18]
  2. 2Davis, J. M. (1974) Dose equivalence of the antipsychotic drugs. J. Psychiatr. Res., 11, 65–69[19]
  3. 3Woods, S. W. (2003) Chlorpromazine equivalent doses for the newer atypical antipsychotics. J. Clin. Psychiatry, 64, 663–667. [20]
  4. 4Kane, J. M., Aguglia, E., Altamura, A. C., et al (1998) Guidelines for depot antipsychotic treatment in schizophrenia. European Neuropsychopharmacology Consensus Conference in Siena, Italy. Eur. Neuropsychopharmacol., 8, 55–66. [21]
  5. 5WHO Collaborating Centre for Drug Statistics Methodology (2005) ATC Index with DDDs. [22]
  6. 6 Bai YM et al, Equivalent Switching Dose From Oral Risperidone to Risperidone Long-Acting Injection: A 48-Week Randomized, Prospective, Single-Blind Pharmacokinetic Study. J Clin Psychiatry 2007;68:1218–1225. [24].
  7. 7Administration Route: O: oral, P: peroral.
  8. The chlorpromazine equivalent doses of levomepromazine, dixyrazine, sertindol and perphenazine decanoate are not adequately defined in the literature, and chlorpromazine equivalent dose is calculated from the DDD.