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Table 2 Means (SD) of secondary outcome variables as a function of study visit and treatment group.

From: Maintenance treatment of adolescent bipolar disorder: open study of the effectiveness and tolerability of quetiapine

Treatment Group Study Visit
  VE V2 V5 V8 V9 V12 V15 V18
CGI-S
Combination 1.80
(0.84)
1.40
(0.55)
1.60
(0.55)
1.20
(0.45)
1.80
(0.45)
1.60
(0.55)
1.40
(0.55)
1.40
(0.55)
Monotherapy 2.46
(0.66)
1.92
(0.86)
1.46
(0.66)
1.54
(0.66)
1.38
(0.65)
1.46
(0.52)
1.54
(0.66)
1.38
(0.51)
Total 2.28
(0.75)
1.78
(0.81)
1.50
(0.62)
1.44
(0.62)
1.50
(0.62)
1.50
(0.51)
1.50
(0.62)
1.39
(0.50)
CGAS
Combination 79.20
(2.39)
83.00
(2.74)
81.00
(5.47)
82.00
(5.70)
79.00
(2.24)
80.00
(6.12)
83.00
(4.47)
84.00
(2.24)
Monotherapy 73.54
(8.23)
78.84
(7.68)
79.23
(7.86)
80.38
(7.21)
82.38
(8.30)
83.46
(3.15)
82.69
(6.33)
82.38
(3.84)
Total 75.11
(7.48)
80.00
(6.85)
79.72
(7.16)
80.83
(6.69)
81.44
(7.22)
82.50
(4.28)
82.77
(5.74)
82.83
(3.48)
MADRS
Combination 9.40
(6.15)
4.40
(2.88)
4.20
(4.08)
4.80
(4.76)
6.60
(3.91)
5.60
(2.88)
3.00
(3.00)
2.80
(2.28)
Monotherapy 9.15
(6.01)
5.54
(6.03)
3.85
(4.27)
4.54
(3.62)
3.15
(3.55)
3.92
(3.01)
3.46
(3.30)
4.15
(3.84)
Total 9.22
(5.86)
5.22
(5.28)
3.94
(4.10)
4.61
(3.82)
4.11
(3.87)
4.39
(2.99)
3.33
(3.14)
3.78
(3.47)
YMRS
Combination 0.60
(1.34)
0.20
(0.45)
2.20
(3.35)
1.40
(1.67)
2.40
(3.78)
0.40
(0.55)
0.40
(0.89)
0.80
(0.84)
Monotherapy 1.92
(3.04)
1.08
(1.04)
0.77
(1.69)
1.31
(2.06)
0.85
(1.57)
1.31
(1.84)
1.00
(2.24)
1.54
(2.11)
Total 1.56
(2.71)
0.83
(0.98)
1.17
(2.25)
1.33
(1.91)
1.28
(2.37)
1.06
(1.62)
0.83
(1.94)
1.33
(1.84)
  1. CGI-S – Clinical Global Impression Severity
  2. CGAS – Clinical Global Assessment Scale
  3. MADRS – Montgomery Asperg Depression Rating Scale
  4. YMRS – Young Mania Rating Scale