Skip to main content

Table 2 Annual acute-care service usea for switchers and continuers on the initial antipsychotic

From: Clinical and economic ramifications of switching antipsychotics in the treatment of schizophrenia

  Patients continuing with their initial antipsychotics (N = 376) Patients switching antipsychotics (N = 156) p-value
Total Days in Study 110,482 52,288  
Mean Days in Study per patient, days 293.8 335.2  
Hospitalization    
   % of patients 16.0 26.3 <.001
   Duration, days 1215 996  
Rateb 1.10% 1.90% .014
   Number of hospital admissions 115 78  
Ratec 0.11% 0.15% .013
Partial hospitalization/day treatment centers    
   % of patients 10.6 18.0 .054
   Duration, days 3,657 1,561  
Rateb 3.35% 3.04% .491
  Patients continuing with their initial antipsychotics (N = 376) Patients switching antipsychotics (N = 156) p-value
   Number of admissions to partial hospitals/day treatment centers 65 45  
Ratec 0.06% 0.09% .306
Crisis service    
   % of patients 12.0 18.0 <.001
   Number of admissions 78 97  
Rateb 0.07% 0.20% .011
   Any acute-care service    
   % of patients 28.5 42.3 <.001
   Number of admissions 258 220  
Ratec 0.24% 0.44% <.001
  1. p values based on propensity score adjusted bootstrap resampling.
  2. aExcluding patients with any crisis event at baseline.
  3. bRate = number of days with each service divided by the total number of days in the study.
  4. cRate = number of admissions divided by the total number of days of treatment
  5. Note: the denominator for the rate of partial hospitalization/day treatment days excludes hospitalization days. The denominator for the rate of crisis days excludes hospitalization and partial hospitalization/day treatment days. The denominator for admissions also excludes non-admission hospitalizations and partial hospital/day treatment days.