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Table 3 Significant biological terms in each comparison between typical AP vs. control, atypical AP vs. control, and typical AP vs. atypical AP.

From: Effects of typical and atypical antipsychotic drugs on gene expression profiles in the liver of schizophrenia subjects

Comparison

Category

Term

Count

%

P-Value

Typical vs. Ctrl

SP_PIR_KEYWORDS

Nuclear protein

70

21%

3.75E-07

Typical vs. Ctrl

GOTERM_BP_ALL

Response to stress

39

12%

4.49E-06

Typical vs. Ctrl

SP_PIR_KEYWORDS

Phosphorylation

46

14%

1.13E-05

Typical vs. Ctrl

INTERPRO_NAME

Basic-leucine zipper (bZIP) transcription factor

8

2%

1.46E-05

Typical vs. Ctrl

GOTERM_MF_ALL

Protein binding

97

29%

1.56E-05

Atypical vs. Ctrl

SP_PIR_KEYWORDS

ER-golgi transport

6

11%

6.19E-08

Atypical vs. Ctrl

GOTERM_CC_ALL

Cytoplasm

26

46%

7.84E-08

Atypical vs. Ctrl

GOTERM_BP_ALL

ER to Golgi vesicle-mediated transport

6

11%

2.86E-07

Atypical vs. Ctrl

SP_PIR_KEYWORDS

Endoplasmic reticulum

9

16%

1.96E-06

Atypical vs. Ctrl

GOTERM_BP_ALL

Golgi vesicle transport

6

11%

2.12E-06

Typical vs. Atypical

GOTERM_BP_ALL

Cellular lipid metabolism

13

10%

9.59E-05

Typical vs. Atypical

GOTERM_BP_ALL

Lipid biosynthesis

9

7%

1.14E-04

Typical vs. Atypical

GOTERM_BP_ALL

Lipid metabolism

14

10%

2.34E-04

Typical vs. Atypical

GOTERM_CC_ALL

Intracellular membrane-bound organelle

54

40%

3.03E-04

Typical vs. Atypical

GOTERM_CC_ALL

Mitochondrion

14

10%

3.66E-04

  1. A set of significant genes (FC>1.3 and p < 0.001) in each comparison was used in the DAVID functional annotation analyses.