Thyroid function in clinical subtypes of major depression: an exploratory study

BMC Psychiatry

Table 1 1-way MANCOVA between the diagnostic groups in terms of thyroid results, with age, 2-way MANCOVA between the short term outcome (factor 1) and diagnostic groups (factor 2) in terms of thyroid results

	Wilks' Lambda	Rao's R	df 1	Df 2	p-level
1-Way MANCOVA 1: Type of depression
1	0.325	5.052	21	221	*0.000*
2-Way MANCOVA 1: Outcome 2: Type of depression
1	0.430	2.835	7	15	0.043
2	0.073	5.772	14	30	*0.000*
12	0.275	1.942	14	30	0.062
	Normal Controls N = 60		Depressed patients N = 30		Atypical features N = 10		Melancholic features N = 12		Undifferentiated N = 8		Responders N = 19		Partial responders N = 11
	Mean	S.D	Mean	S.D	Mean	S.D	Mean	S.D	Mean	S.D	Mean	S.D	Mean	S.D
FT4	16.32	2.69	14.59	1,59	15.50	1.28	14.15	1.45	14.13	1.83	14.04	1.39	15.55	1.52
FT3	6.03	1.56	5.85	1,00	6.57	1.16	5.30	0.50	5.76	0.85	5.83	1.18	5.88	0.61
TSH	1.31	0.74	1.52	1,21	0.92	0.33	1.42	0.71	2.43	1.92	1.58	0.99	1.43	1.57
TBII	0.89	1.16	8.67	7,93	7.64	3.13	6.31	1.30	13.49	14.41	7.66	2.29	10.40	12.95
TMA	18.80	3.42	124.86	295,08	272.14	477.98	51.35	66.94	51.04	116.07	151.17	362.54	79.43	111.13
TA	15.26	8.52	20.41	9,91	18.23	4.51	23.72	13.93	18.19	6.71	19.05	5.71	22.77	14.72
T4/T3 ratio	2.81	0.64	2.54	0,33	2.41	0.39	2.68	0.31	2.46	0.20	2.46	0.35	2.66	0.28

In both analyses, age, the presence of anxiety disorder and the presence of personality disorder as covariates. Scheffe test served as post-hoc test

ISSN: 1471-244X