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Table 6 Association between APOE epsilon alleles and MMSE ≤25 (carriers vs. non-carriers)

From: Influence of multiple APOE genetic variants on cognitive function in a cohort of older men – results from the Normative Aging Study

 

Unadjusted

Fully adjusted*

Allele

OR

(95% CI)

p

OR

(95% CI)

p

ε1

0.498

(0.112 - 2.212)

0.359

0.615

(0.131 - 2.893)

0.538

ε2

0.781

(0.455 - 1.342)

0.371

0.784

(0.443 - 1.386)

0.402

ε2

2.043

(0.788 - 5.293)

0.141

2.103

(0.781 - 5.6603)

0.141

ε4

0.639

(0.425 - 0.961)

0.032

0.612

(0.398 - 0.940)

0.024

  1. OR = Odds Ratio; 95%CI = 95% Confidence Interval.
  2. *Adjusted for race, education, alcohol consumption, physical activity, diabetes mellitus, fish consumption, computer experience, English as a first language, cholesterol, smoking, obesity, and hypertension. Bold highlights statistical significant result.
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BMC Psychiatry

ISSN: 1471-244X

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