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Table 3 Overview of results with no significant differences

From: A systematic review of Chinese randomized clinical trials of SSRI treatment of depression

Remission

MH risk ratio (95%CI)

No. of comparisons

No. of subjects

Fluoxetine vs. any other SSRIs

0.98 (0.83-1.17)

6

576

Citalopram vs. any other SSRIs

0.92 (0.80-1.05)

8

753

Sertraline vs. any other SSRIs

0.93 (0.71-1.24)

1

34

SSRI vs. TCM

0.98 (0.80-1.20)

4

995

SSRI vs. teCA

1.00 (0.78-1.27)

5

426

SSRI vs. NARI

1.03 (0.80-1.32)

3

363

SSRI vs. NDRI

1.39 (0.79-2.47)

2

140

SSRI vs. SARI

1.06 (0.80-1.39)

1

240

SSRI vs. SNRI

0.96 (0.85-1.08)

4

370

Geriatric SSRI vs. TCA

1.25 (0.89-1.75)

4

154

Geriatric SSRI vs. teCA

1.16 (0.87-1.55)

3

214

Non-geriatric SSRI vs. teCA

0.73 (0.47-1.11)

2

212

Response

MH risk ratio (95% CI)

No. of comparisons

No. of subjects

Fluoxetine vs. any other SSRIs

0.97 (0.89-1.06)

7

648

Citalopram vs. any other SSRIs

1.02 (0.95-1.10)

8

803

Sertraline vs. any other SSRIs

1.06 (0.82-1.37)

1

92

SSRI vs. TCM

1.04 (0.98-1.11)

7

2008

SSRI vs. teCA

1.02 (0.85-1.24)

5

426

SSRI vs. NARI

1.07 (0.92-1.23)

2

300

SSRI vs. NDRI

1.03 (0.89-1.18)

3

309

SSRI vs. SARI

1.03 (0.90-1.19)

1

240

SSRI vs. SNRI

0.96 (0.90-1.03)

5

614

Geriatric SSRI vs. TCA

1.09 (0.92-1.29)

4

154

Geriatric SSRI vs. teCA

1.07 (0.90-1.28)

3

214

Non-geriatric SSRI vs. teCA

0.90 (0.49-1.65)

2

212

Dropout rates due to side effects

MH risk ratio (95% CI)

No. of comparisons

No. of subjects

Fluoxetine vs. any other SSRIs

0.88 (0.27-2.79)

1

240

Citalopram vs. any other SSRIs

1.70 (0.65-4.45)

4

600

SSRI vs. TCA

0.51 (0.25-1.05)

9

590

SSRI vs. TCM

0.66 (0.17-2.52)

3

326

SSRI vs. teCA

0.60 (0.28-1.30)

2

194

SSRI vs. NARI

0.25 (0.03-2.20)

1

240

SSRI vs. Placebo

3.00 (0.13-71.00)

1

64

SSRI vs. SNRI

1.58 (0.21-12.20)

2

82

Geriatric SSRI vs. TCA

0.29 (0.05-1.79)

2

100

Non-geriatric SSRI vs. TCA

0.57 (0.26-1.23)

7

490

Geriatric SSRI vs. teCA

0.50 (0.05-5.23)

1

62

Non-geriatric SSRI vs. teCA

0.62 (0.27-1.39)

1

132

  1. MH: Mantel-Haenszel.
  2. CI: confidence interval.
  3. SSRI: Selective serotonin reuptake inhibitor.
  4. TCA: tricyclic antidepressant.
  5. teCA: Tetracyclic antidepressant.
  6. TCM: Traditional Chinese Medicine.
  7. NARI: Norepinephrine Reuptake Inhibitor.
  8. NDRI: Norepinephrine and Dopamine Reuptake Inhibitor.
  9. SARI: Serotonin Antagonist and Reuptake Inhibitor.
  10. SNRI: Selective Noradrenaline Reuptake Inhibitor.